{"code":"C49.8","type":"code","title":"Malignant neoplasm of overlapping sites of connective and soft tissue","codeAlso":[],"includes":["malignant neoplasm of blood vessel","malignant neoplasm of bursa","malignant neoplasm of cartilage","malignant neoplasm of fascia","malignant neoplasm of fat","malignant neoplasm of ligament, except uterine","malignant neoplasm of lymphatic vessel","malignant neoplasm of muscle","malignant neoplasm of synovia","malignant neoplasm of tendon (sheath)"],"modern_v":"official26","codeFirst":[],"excludes1":["malignant neoplasm of cartilage (of):","articular (C40-C41)","larynx (C32.3)","nose (C30.0)","malignant neoplasm of connective tissue of breast (C50.-)"],"excludes2":["Kaposi's sarcoma of soft tissue (C46.1)","malignant neoplasm of heart (C38.0)","malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)","malignant neoplasm of peritoneum (C48.2)","malignant neoplasm of retroperitoneum (C48.0)","malignant neoplasm of uterine ligament (C57.3)","mesothelioma (C45.-)"],"isBillable":true,"fyEffectivity":{"fy2026":true,"fy2027":true,"billableFy2026":true,"billableFy2027":true},"sibling_codes":["C49","C49.0","C49.1","C49.2","C49.3","C49.4","C49.5","C49.6","C49.9","C49.A","C49.A0","C49.A1","C49.A2","C49.A3","C49.A4","C49.A5","C49.A9"],"inclusionTerms":["Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue"],"sibling_titles":{"code":"C49.A9","title":"Gastrointestinal stromal tumor of other sites","isBillable":true},"useAdditionalCode":[],"clinicalDefinition":"Malignant neoplasm of overlapping sites of connective and soft tissue is a billable ICD-10-CM diagnosis code (C49.8). Includes: malignant neoplasm of blood vessel; malignant neoplasm of bursa; malignant neoplasm of cartilage; malignant neoplasm of fascia; malignant neoplasm of fat; malignant neoplasm of ligament, except uterine; malignant neoplasm of lymphatic vessel; malignant neoplasm of muscle; malignant neoplasm of synovia; malignant neoplasm of tendon (sheath).","officialDefinition":"Malignant neoplasm of overlapping sites of connective and soft tissue is a billable ICD-10-CM diagnosis code (C49.8). Includes: malignant neoplasm of blood vessel; malignant neoplasm of bursa; malignant neoplasm of cartilage; malignant neoplasm of fascia; malignant neoplasm of fat; malignant neoplasm of ligament, except uterine; malignant neoplasm of lymphatic vessel; malignant neoplasm of muscle; malignant neoplasm of synovia; malignant neoplasm of tendon (sheath). Inclusion terms: Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue. Excludes1 (not coded here): malignant neoplasm of cartilage (of):; articular (C40-C41); larynx (C32.3); nose (C30.0); malignant neoplasm of connective tissue of breast (C50.-). Excludes2 (not included here): Kaposi's sarcoma of soft tissue (C46.1); malignant neoplasm of heart (C38.0); malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-); malignant neoplasm of peritoneum (C48.2); malignant neoplasm of retroperitoneum (C48.0); malignant neoplasm of uterine ligament (C57.3); mesothelioma (C45.-).","seventhCharacterInstructions":[],"workflowProtocols":[],"guidelines":{"whenToUse":[],"whenNotToUse":[],"commonBillingMistakes":[],"codeComparisons":[],"documentationChecklist":[]},"domainLandscape":{"summary":"Primary diagnostic domain and clinical landscape evaluation.","keyCategories":[],"diagnosticContinuum":"Progression continuum from acute presentation to resolution."},"children":[],"hierarchy":[],"relatedCodes":[],"relevantCPTCodes":[],"documentationTips":[],"caseStudies":[],"description":"","overview":"","noteProvenance":{"malignant neoplasm of cartilage (of):":"C49","articular (C40-C41)":"C49","larynx (C32.3)":"C49","nose (C30.0)":"C49","malignant neoplasm of connective tissue of breast (C50.-)":"C49","Kaposi's sarcoma of soft tissue (C46.1)":"C49","malignant neoplasm of heart (C38.0)":"C49","malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)":"C49","malignant neoplasm of peritoneum (C48.2)":"C49","malignant neoplasm of retroperitoneum (C48.0)":"C49","malignant neoplasm of uterine ligament (C57.3)":"C49","mesothelioma (C45.-)":"C49","malignant neoplasm of blood vessel":"C49","malignant neoplasm of bursa":"C49","malignant neoplasm of cartilage":"C49","malignant neoplasm of fascia":"C49","malignant neoplasm of fat":"C49","malignant neoplasm of ligament, except uterine":"C49","malignant neoplasm of lymphatic vessel":"C49","malignant neoplasm of muscle":"C49","malignant neoplasm of synovia":"C49","malignant neoplasm of tendon (sheath)":"C49"},"hcc":{"mapped":true,"model":"CMS-HCC V28","paymentYear":"2026","categories":[{"hcc":"21","label":"Lymphoma and Other Cancers","family":"Neoplasm","suppresses":[{"hcc":"22","label":"Bladder, Colorectal, and Other Cancers"},{"hcc":"23","label":"Prostate, Breast, and Other Cancers and Tumors"}]}],"otherModels":[{"model":"CMS-HCC V22","hcc":"10"},{"model":"RxHCC V08","hcc":"22"}]}}