{"code":"E80","type":"category","title":"Disorders of porphyrin and bilirubin metabolism","codeAlso":[],"includes":["defects of catalase and peroxidase"],"modern_v":"official26","codeFirst":[],"excludes1":["androgen insensitivity syndrome (E34.5-)","congenital adrenal hyperplasia (E25.0)","hemolytic anemias attributable to enzyme disorders (D55.-)","Marfan syndrome (Q87.4-)","5-alpha-reductase deficiency (E29.1)"],"excludes2":["Ehlers-Danlos syndromes (Q79.6-)"],"isBillable":false,"fyEffectivity":{"fy2026":true,"fy2027":true,"billableFy2026":false,"billableFy2027":false},"sibling_codes":["E80.0","E80.1","E80.2","E80.20","E80.21","E80.29","E80.3","E80.4","E80.5","E80.6","E80.7"],"inclusionTerms":[],"sibling_titles":{"code":"E80.7","title":"Disorder of bilirubin metabolism, unspecified","isBillable":true},"useAdditionalCode":[],"clinicalDefinition":"Disorders of porphyrin and bilirubin metabolism is a non-billable ICD-10-CM category code (E80). A more specific billable subcode must be selected for claims submission. Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","officialDefinition":"Disorders of porphyrin and bilirubin metabolism is a non-billable ICD-10-CM category code (E80). A more specific billable subcode must be selected for claims submission. Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","seventhCharacterInstructions":[],"workflowProtocols":[],"guidelines":{"whenToUse":[],"whenNotToUse":[],"commonBillingMistakes":[],"codeComparisons":[],"documentationChecklist":[]},"domainLandscape":{"summary":"Primary diagnostic domain and clinical landscape evaluation.","keyCategories":[],"diagnosticContinuum":"Progression continuum from acute presentation to resolution."},"children":[{"code":"E80.0","title":"Hereditary erythropoietic porphyria","description":"Hereditary erythropoietic porphyria is a billable ICD-10-CM diagnosis code (E80.0). Includes: defects of catalase and peroxidase. Inclusion terms: Congenital erythropoietic porphyria; Erythropoietic protoporphyria. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.0-hereditary-erythropoietic-porphyria"},{"code":"E80.1","title":"Porphyria cutanea tarda","description":"Porphyria cutanea tarda is a billable ICD-10-CM diagnosis code (E80.1). Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.1-porphyria-cutanea-tarda"},{"code":"E80.2","title":"Other and unspecified porphyria","description":"Other and unspecified porphyria is a non-billable ICD-10-CM category code (E80.2). A more specific billable subcode must be selected for claims submission. Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":false,"slug":"e80.2-other-and-unspecified-porphyria"},{"code":"E80.20","title":"Unspecified porphyria","description":"Unspecified porphyria is a billable ICD-10-CM diagnosis code (E80.20). Includes: defects of catalase and peroxidase. Inclusion terms: Porphyria NOS. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.20-unspecified-porphyria"},{"code":"E80.21","title":"Acute intermittent (hepatic) porphyria","description":"Acute intermittent (hepatic) porphyria is a billable ICD-10-CM diagnosis code (E80.21). Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.21-acute-intermittent-hepatic-porphyria"},{"code":"E80.29","title":"Other porphyria","description":"Other porphyria is a billable ICD-10-CM diagnosis code (E80.29). Includes: defects of catalase and peroxidase. Inclusion terms: Hereditary coproporphyria. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.29-other-porphyria"},{"code":"E80.3","title":"Defects of catalase and peroxidase","description":"Defects of catalase and peroxidase is a billable ICD-10-CM diagnosis code (E80.3). Includes: defects of catalase and peroxidase. Inclusion terms: Acatalasia [Takahara]. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.3-defects-of-catalase-and-peroxidase"},{"code":"E80.4","title":"Gilbert syndrome","description":"Gilbert syndrome is a billable ICD-10-CM diagnosis code (E80.4). Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.4-gilbert-syndrome"},{"code":"E80.5","title":"Crigler-Najjar syndrome","description":"Crigler-Najjar syndrome is a billable ICD-10-CM diagnosis code (E80.5). Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.5-crigler-najjar-syndrome"},{"code":"E80.6","title":"Other disorders of bilirubin metabolism","description":"Other disorders of bilirubin metabolism is a billable ICD-10-CM diagnosis code (E80.6). Includes: defects of catalase and peroxidase. Inclusion terms: Dubin-Johnson syndrome; Rotor's syndrome. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.6-other-disorders-of-bilirubin-metabolism"},{"code":"E80.7","title":"Disorder of bilirubin metabolism, unspecified","description":"Disorder of bilirubin metabolism, unspecified is a billable ICD-10-CM diagnosis code (E80.7). Includes: defects of catalase and peroxidase. Excludes1 (not coded here): androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-); Marfan syndrome (Q87.4-); 5-alpha-reductase deficiency (E29.1). Excludes2 (not included here): Ehlers-Danlos syndromes (Q79.6-).","isBillable":true,"slug":"e80.7-disorder-of-bilirubin-metabolism-unspecified"}],"hierarchy":[],"relatedCodes":[],"relevantCPTCodes":[],"documentationTips":[],"caseStudies":[],"description":"","overview":""}