{"code":"K52.21","type":"code","title":"Food protein-induced enterocolitis syndrome","codeAlso":[],"includes":["noninfective inflammatory bowel disease"],"modern_v":"official26","codeFirst":[],"excludes1":["irritable bowel syndrome (K58.-)","megacolon (K59.3-)"],"excludes2":["allergic eosinophilic colitis (K52.82)","allergic eosinophilic esophagitis (K20.0)","allergic eosinophilic gastritis (K52.81)","allergic eosinophilic gastroenteritis (K52.81)"],"isBillable":true,"fyEffectivity":{"fy2026":true,"fy2027":true,"billableFy2026":true,"billableFy2027":true},"sibling_codes":["K52","K52.0","K52.1","K52.2","K52.22","K52.29","K52.3","K52.8","K52.81","K52.82","K52.83","K52.831","K52.832","K52.838","K52.839","K52.89","K52.9"],"inclusionTerms":["FPIES"],"sibling_titles":{"code":"K52.9","title":"Noninfective gastroenteritis and colitis, unspecified","isBillable":true},"useAdditionalCode":["code for hypovolemic shock, if present (R57.1)","code to identify type of food allergy (Z91.01-, Z91.02-)"],"clinicalDefinition":"Food protein-induced enterocolitis syndrome is a billable ICD-10-CM diagnosis code (K52.21). Includes: noninfective inflammatory bowel disease. Inclusion terms: FPIES. Excludes1 (not coded here): irritable bowel syndrome (K58.-); megacolon (K59.3-). Excludes2 (not included here): allergic eosinophilic colitis (K52.82); allergic eosinophilic esophagitis (K20.0); allergic eosinophilic gastritis (K52.81); allergic eosinophilic gastroenteritis (K52.81). Use additional code: code for hypovolemic shock, if present (R57.1); code to identify type of food allergy (Z91.01-, Z91.02-).","officialDefinition":"Food protein-induced enterocolitis syndrome is a billable ICD-10-CM diagnosis code (K52.21). Includes: noninfective inflammatory bowel disease. Inclusion terms: FPIES. Excludes1 (not coded here): irritable bowel syndrome (K58.-); megacolon (K59.3-). Excludes2 (not included here): allergic eosinophilic colitis (K52.82); allergic eosinophilic esophagitis (K20.0); allergic eosinophilic gastritis (K52.81); allergic eosinophilic gastroenteritis (K52.81). Use additional code: code for hypovolemic shock, if present (R57.1); code to identify type of food allergy (Z91.01-, Z91.02-).","seventhCharacterInstructions":[],"workflowProtocols":[],"guidelines":{"whenToUse":[],"whenNotToUse":[],"commonBillingMistakes":[],"codeComparisons":[],"documentationChecklist":[]},"domainLandscape":{"summary":"Primary diagnostic domain and clinical landscape evaluation.","keyCategories":[],"diagnosticContinuum":"Progression continuum from acute presentation to resolution."},"children":[],"hierarchy":[],"relatedCodes":[],"relevantCPTCodes":[],"documentationTips":[],"caseStudies":[],"description":"","overview":""}