{"code":"R65.11","type":"code","title":"Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction","codeAlso":[],"includes":[],"modern_v":"official26","codeFirst":["underlying condition, such as:","heatstroke (T67.0-)","injury and trauma (S00-T88)"],"excludes1":["sepsis- code to infection","severe sepsis (R65.2)"],"excludes2":[],"isBillable":true,"fyEffectivity":{"fy2026":true,"fy2027":true,"billableFy2026":true,"billableFy2027":true},"sibling_codes":["R65","R65.1","R65.10","R65.2","R65.20","R65.21"],"inclusionTerms":[],"sibling_titles":{"code":"R65.21","title":"Severe sepsis with septic shock","isBillable":true},"useAdditionalCode":["code to identify specific acute organ dysfunction, such as:","acute kidney failure (N17.-)","acute respiratory failure (J96.0-)","critical illness myopathy (G72.81)","critical illness polyneuropathy (G62.81)","disseminated intravascular coagulopathy [DIC] (D65)","encephalopathy (metabolic) (septic) (G93.41)","hepatic failure (K72.0-)"],"clinicalDefinition":"Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction is a billable ICD-10-CM diagnosis code (R65.11). Excludes1 (not coded here): sepsis- code to infection; severe sepsis (R65.2). Code first: underlying condition, such as:; heatstroke (T67.0-); injury and trauma (S00-T88). Use additional code: code to identify specific acute organ dysfunction, such as:; acute kidney failure (N17.-); acute respiratory failure (J96.","officialDefinition":"Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction is a billable ICD-10-CM diagnosis code (R65.11). Excludes1 (not coded here): sepsis- code to infection; severe sepsis (R65.2). Code first: underlying condition, such as:; heatstroke (T67.0-); injury and trauma (S00-T88). Use additional code: code to identify specific acute organ dysfunction, such as:; acute kidney failure (N17.-); acute respiratory failure (J96.0-); critical illness myopathy (G72.81); critical illness polyneuropathy (G62.81); disseminated intravascular coagulopathy [DIC] (D65); encephalopathy (metabolic) (septic) (G93.41); hepatic failure (K72.0-).","seventhCharacterInstructions":[],"workflowProtocols":[],"guidelines":{"whenToUse":[],"whenNotToUse":[],"commonBillingMistakes":[],"codeComparisons":[],"documentationChecklist":[]},"domainLandscape":{"summary":"Primary diagnostic domain and clinical landscape evaluation.","keyCategories":[],"diagnosticContinuum":"Progression continuum from acute presentation to resolution."},"children":[],"hierarchy":[],"relatedCodes":[],"relevantCPTCodes":[],"documentationTips":[],"caseStudies":[],"description":"","overview":""}