{"code":"T45.8X4D","type":"code","title":"Poisoning by other primarily systemic and hematological agents, undetermined, subsequent encounter","codeAlso":[],"includes":["adverse effect of correct substance properly administered","poisoning by overdose of substance","poisoning by wrong substance given or taken in error","underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed"],"modern_v":"official26","codeFirst":[", for adverse effects, the nature of the adverse effect, such as:","adverse effect NOS (T88.7)","aspirin gastritis (K29.-)","blood disorders (D56-D76)","contact dermatitis (L23-L25)","dermatitis due to substances taken internally (L27.-)","nephropathy (N14.0-N14.2)"],"excludes1":["toxic reaction to local anesthesia in pregnancy (O29.3-)"],"excludes2":["poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1)","poisoning by, adverse effect of and underdosing of iron (T45.4)","transfusion reactions (T80.-)","abuse and dependence of psychoactive substances (F10-F19)","abuse of non-dependence-producing substances (F55.-)","immunodeficiency due to drugs (D84.821)","drug reaction and poisoning affecting newborn (P00-P96)","pathological drug intoxication (inebriation) (F10-F19)"],"isBillable":true,"fyEffectivity":{"fy2026":true,"fy2027":true,"billableFy2026":true,"billableFy2027":true},"inclusionTerms":[],"useAdditionalCode":["code(s) to specify:","manifestations of poisoning","underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)","underdosing of medication regimen (Z91.12-, Z91.13-)"],"clinicalDefinition":"Poisoning by other primarily systemic and hematological agents, undetermined, subsequent encounter is a billable ICD-10-CM diagnosis code (T45.8X4D). Includes: adverse effect of correct substance properly administered; poisoning by overdose of substance; poisoning by wrong substance given or taken in error; underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed. Excludes1 (not coded here): toxic reaction to local anesthesia in pregnancy (O29.3-).","officialDefinition":"Poisoning by other primarily systemic and hematological agents, undetermined, subsequent encounter is a billable ICD-10-CM diagnosis code (T45.8X4D). Includes: adverse effect of correct substance properly administered; poisoning by overdose of substance; poisoning by wrong substance given or taken in error; underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed. Excludes1 (not coded here): toxic reaction to local anesthesia in pregnancy (O29.3-). Excludes2 (not included here): poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1); poisoning by, adverse effect of and underdosing of iron (T45.4); transfusion reactions (T80.-); abuse and dependence of psychoactive substances (F10-F19); abuse of non-dependence-producing substances (F55.-); immunodeficiency due to drugs (D84.821); drug reaction and poisoning affecting newborn (P00-P96); pathological drug intoxication (inebriation) (F10-F19). Code first: , for adverse effects, the nature of the adverse effect, such as:; adverse effect NOS (T88.7); aspirin gastritis (K29.-); blood disorders (D56-D76); contact dermatitis (L23-L25); dermatitis due to substances taken internally (L27.-); nephropathy (N14.0-N14.2). Use additional code: code(s) to specify:; manifestations of poisoning; underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9); underdosing of medication regimen (Z91.12-, Z91.13-). 7th character: The appropriate 7th character is to be added to each code from category T45.","seventhCharacterInstructions":["The appropriate 7th character is to be added to each code from category T45"],"workflowProtocols":[],"guidelines":{"whenToUse":[],"whenNotToUse":[],"commonBillingMistakes":[],"codeComparisons":[],"documentationChecklist":[]},"domainLandscape":{"summary":"Primary diagnostic domain and clinical landscape evaluation.","keyCategories":[],"diagnosticContinuum":"Progression continuum from acute presentation to resolution."},"children":[],"hierarchy":[],"relatedCodes":[],"relevantCPTCodes":[],"documentationTips":[],"caseStudies":[],"description":"","overview":"","noteProvenance":{"toxic reaction to local anesthesia in pregnancy (O29.3-)":"T45","abuse and dependence of psychoactive substances (F10-F19)":"T45","abuse of non-dependence-producing substances (F55.-)":"T45","immunodeficiency due to drugs (D84.821)":"T45","drug reaction and poisoning affecting newborn (P00-P96)":"T45","pathological drug intoxication (inebriation) (F10-F19)":"T45",", for adverse effects, the nature of the adverse effect, such as:":"T45","adverse effect NOS (T88.7)":"T45","aspirin gastritis (K29.-)":"T45","blood disorders (D56-D76)":"T45","contact dermatitis (L23-L25)":"T45","dermatitis due to substances taken internally (L27.-)":"T45","nephropathy (N14.0-N14.2)":"T45","code(s) to specify:":"T45","manifestations of poisoning":"T45","underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)":"T45","underdosing of medication regimen (Z91.12-, Z91.13-)":"T45","adverse effect of correct substance properly administered":"T45","poisoning by overdose of substance":"T45","poisoning by wrong substance given or taken in error":"T45","underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed":"T45","poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1)":"T45.8","poisoning by, adverse effect of and underdosing of iron (T45.4)":"T45.8","transfusion reactions (T80.-)":"T45.8","Poisoning by, adverse effect of and underdosing of liver preparations and other antianemic agents":"T45.8","Poisoning by, adverse effect of and underdosing of natural blood and blood products":"T45.8","Poisoning by, adverse effect of and underdosing of plasma substitute":"T45.8"},"hcc":{"mapped":false,"model":"CMS-HCC V28","paymentYear":"2026","categories":[],"otherModels":[]}}