C88.20 is the authoritative medical code for Heavy chain disease not having achieved remission. This classification is used in medical billing and clinical recording to specify the clinical criteria for heavy chain disease not having achieved remission (ICD-10-CM C88.20), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Heavy chain disease not having achieved remission is a billable ICD-10-CM diagnosis code C88.20. Inclusion terms: Franklin disease NOS; Franklin disease not having achieved remission; Franklin disease with failed remission; Gamma heavy chain disease NOS; Gamma heavy chain disease not having achieved remission; Gamma heavy chain disease with failed remission; Heavy chain disease NOS; Heavy chain disease with failed remissionMu heavy chain disease not having achieved remission; Mu heavy chain disease NOS; Mu heavy chain disease not having achieved remission; Mu heavy chain disease with failed remission. Excludes1 (not coded here): B-cell lymphoma, unspecified C85.1-; personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues Z85.79. Excludes2 (not included here): Kaposi's sarcoma of lymph nodes C46.3; secondary and unspecified neoplasm of lymph nodes C77.-; secondary neoplasm of bone marrow C79.52; secondary neoplasm of spleen C78.89.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for C88.20 in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Franklin disease NOS
- Franklin disease not having achieved remission
- Franklin disease with failed remission
- Gamma heavy chain disease NOS
- Gamma heavy chain disease not having achieved remission
- Gamma heavy chain disease with failed remission
- Heavy chain disease NOS
- Heavy chain disease with failed remissionMu heavy chain disease not having achieved remission
- Mu heavy chain disease NOS
- Mu heavy chain disease not having achieved remission
- Mu heavy chain disease with failed remission
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- B-cell lymphoma, unspecified C85.1-
- personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues Z85.79
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Kaposi's sarcoma of lymph nodes C46.3
- secondary and unspecified neoplasm of lymph nodes C77.-
- secondary neoplasm of bone marrow C79.52
- secondary neoplasm of spleen C78.89
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with C88.20?
Per Excludes1 instructions, C88.20 must not be reported with: B-cell lymphoma, unspecified (C85.1-); personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79).
Can C88.20 be reported alongside related conditions?
Per Excludes2 instructions, C88.20 and the following may both be reported when both are present: Kaposi's sarcoma of lymph nodes (C46.3); secondary and unspecified neoplasm of lymph nodes (C77.-); secondary neoplasm of bone marrow (C79.52); secondary neoplasm of spleen (C78.89).
What conditions are included under C88.20?
Heavy chain disease not having achieved remission includes: Franklin disease NOS; Franklin disease not having achieved remission; Franklin disease with failed remission; Gamma heavy chain disease NOS; Gamma heavy chain disease not having achieved remission.
Codes in This Family (18)
Official ICD-10-CM classifications in the same code family as C88.20, with their registry titles.
- C88 — Malignant immunoproliferative diseases and certain other B-cell lymphomas
- C88.0 — Waldenström macroglobulinemia
- C88.00 — Waldenström macroglobulinemia not having achieved remission
- C88.01 — Waldenström macroglobulinemia, in remission
- C88.2 — Heavy chain disease
- C88.21 — Heavy chain disease, in remission
- C88.3 — Immunoproliferative small intestinal disease
- C88.30 — Immunoproliferative small intestinal disease not having achieved remission
- C88.31 — Immunoproliferative small intestinal disease, in remission
- C88.4 — Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
- C88.40 — Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] not having achieved remission
- C88.41 — Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma], in remission
- C88.8 — Other malignant immunoproliferative diseases
- C88.80 — Other malignant immunoproliferative diseases not having achieved remission
- C88.81 — Other malignant immunoproliferative diseases, in remission
- C88.9 — Malignant immunoproliferative disease, unspecified
- C88.90 — Malignant immunoproliferative disease, unspecified not having achieved remission
- C88.91 — Malignant immunoproliferative disease, unspecified, in remission
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:
ICD Code C85.20
Mediastinal (thymic) large B-cell lymphoma, unspecified site
ICD Code C86.20
Enteropathy-type (intestinal) T-cell lymphoma not having achieved remission
ICD Code C92.20
Atypical chronic myeloid leukemia, BCR/ABL-negative, not having achieved remission