E78.49 is the authoritative medical code for Other hyperlipidemia. This classification is used in medical billing and clinical recording to specify the clinical criteria for other hyperlipidemia (ICD-10-CM E78.49), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Other hyperlipidemia is a billable ICD-10-CM diagnosis code E78.49. Inclusion terms: Familial combined hyperlipidemia. Excludes1 (not coded here): sphingolipidosis E75.0-E75.3; androgen insensitivity syndrome E34.5-; congenital adrenal hyperplasia E25.0; hemolytic anemias attributable to enzyme disorders D55.-; Marfan syndrome Q87.4-; 5-alpha-reductase deficiency E29.1. Excludes2 (not included here): Ehlers-Danlos syndromes Q79.6-.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for E78.49 in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Familial combined hyperlipidemia
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- sphingolipidosis E75.0-E75.3
- androgen insensitivity syndrome E34.5-
- congenital adrenal hyperplasia E25.0
- hemolytic anemias attributable to enzyme disorders D55.-
- Marfan syndrome Q87.4-
- 5-alpha-reductase deficiency E29.1
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Ehlers-Danlos syndromes Q79.6-
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with E78.49?
Per official ICD-10-CM Excludes1 instructions, E78.49 must not be reported together with: sphingolipidosis (E75.0-E75.3); androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); hemolytic anemias attributable to enzyme disorders (D55.-).
Can E78.49 be reported alongside related conditions?
Per official ICD-10-CM Excludes2 instructions, E78.49 and the following are not considered part of each other and may both be reported when both conditions are present: Ehlers-Danlos syndromes (Q79.6-).
What conditions are included under E78.49?
Other hyperlipidemia includes: Familial combined hyperlipidemia.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to E78.49 in its code family, with their registry titles.
- E78 — Disorders of lipoprotein metabolism and other lipidemias
- E78.0 — Pure hypercholesterolemia
- E78.01 — Familial hypercholesterolemia
- E78.010 — Homozygous familial hypercholesterolemia [HoFH]
- E78.011 — Heterozygous familial hypercholesterolemia [HeFH]
- E78.019 — Familial hypercholesterolemia, unspecified
- E78.1 — Pure hyperglyceridemia
- E78.2 — Mixed hyperlipidemia
- E78.3 — Hyperchylomicronemia
- E78.4 — Other hyperlipidemia
View all 22 codes in the E78 family
Indexed Clinical Terms (2)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Hyperlipemia, hyperlipidemia, combined, familial
- Hyperlipemia, hyperlipidemia, specified NEC