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B96.22 ICD-10-CM Code: Other specified Shiga toxin-producing Escherichia coli [E. coli] [STEC] as the cause of diseases classified elsewhere

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 867 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH MCC (MDC 18)
  • MS-DRG 868 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH CC (MDC 18)
  • MS-DRG 869 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITHOUT CC/MCC (MDC 18)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Other specified Shiga toxin-producing Escherichia coli [E. coli] [STEC] as the cause of diseases classified elsewhere is a billable ICD-10-CM diagnosis code (B96.22).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for B96.22 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Non-O157 Shiga toxin-producing Escherichia coli [E. coli]
  • Non-O157 Shiga toxin-producing Escherichia coli [E. coli] with known O group

Change history

  • FY2020 — 2019-10-01
    Description revised
    Other specified Shiga toxin-producing Escherichia coli [E. coli] (STEC) as the cause of diseases classified elsewhere → Other specified Shiga toxin-producing Escherichia coli [E. coli] [STEC] as the cause of diseases classified elsewhere
    FY2020 changes
  • FY2020 — 2019-10-01
    Short description revised
    Oth shiga toxin E coli (STEC) causing diseases classd elswhr → Oth shiga toxin E coli [STEC] causing diseases classd elswhr
    FY2020 changes

Verify Before Coding

  • Principal-diagnosis restriction. The Medicare Code Editor lists this code as unacceptable as a principal diagnosis: it describes a circumstance influencing health status rather than a current illness or injury being treated. It is valid as a secondary diagnosis.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of B96.22 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • A00-B99 — Chapter 1: Certain Infectious and Parasitic Diseases (A00-B99) (A00-B99) [Hierarchy]

Referenced by Use Additional Code instructions (10)

  • D59.31 — Infection-associated hemolytic-uremic syndrome [Use Additional Code](via B96.2.-): “E. coli infection (B96.2-)” · check together
  • G00.8 — Other bacterial meningitis [Use Additional Code](via B96.-): “code to further identify organism (B96.-)” · check together
  • J95.851 — Ventilator associated pneumonia [Use Additional Code](via B96.-): “code to identify the organism, if known (B95.-, B96.-, B97.-)” · check together
  • K95.01 — Infection due to gastric band procedure [Use Additional Code](via B96.-): “bacterial and viral infectious agents (B95.-, B96.-)” · check together
  • K95.81 — Infection due to other bariatric procedure [Use Additional Code](via B96.-): “bacterial and viral infectious agents (B95.-, B96.-)” · check together
  • M71.0 — Abscess of bursa [Use Additional Code](via B96.-): “code (B95.-, B96.-) to identify causative organism” · check together
  • M71.1 — Other infective bursitis [Use Additional Code](via B96.-): “code (B95.-, B96.-) to identify causative organism” · check together
  • M72.6 — Necrotizing fasciitis [Use Additional Code](via B96.-): “code (B95.-, B96.-) to identify causative organism” · check together
  • and 2 more

Clinical classification (CCSR)

  • INF003 — Bacterial infections [CCSR]

Potential MS-DRG

  • DRG 867 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH MCC [MS-DRG]: “OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH MCC (MDC 18)”
  • DRG 868 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH CC [MS-DRG]: “OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITH CC (MDC 18)”
  • DRG 869 — OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITHOUT CC/MCC [MS-DRG]: “OTHER INFECTIOUS AND PARASITIC DISEASES DIAGNOSES WITHOUT CC/MCC (MDC 18)”

MDC crossing · procedures

  • MDC 18 — Infectious and Parasitic Diseases, Systemic or Unspecified Sites [MDC crossing]: “Infectious and Parasitic Diseases, Systemic or Unspecified Sites — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • 5A1955Z — Respiratory Ventilation, Greater than 96 Consecutive Hours [Same-MDC procedure]: “Respiratory Ventilation, Greater than 96 Consecutive Hours — grouped in MDC 18, the procedure side of this code's crossing.” · check together

Index entries

  • Escherichia coli, as cause of disease classified elsewhere (E. coli), non-O157 Shiga toxin-producing (with known O group)[Index term]
  • Escherichia coli, as cause of disease classified elsewhere (E. coli), O157:H7 with or without confirmation of Shiga toxin-production, specified NEC[Index term]

Nearest codes (18)

  • B96 — Other bacterial agents as the cause of diseases classified elsewhere [Sibling]
  • B96.0 — Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified elsewhere [Sibling]
  • B96.1 — Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified elsewhere [Sibling]
  • B96.2 — Escherichia coli [E. coli ] as the cause of diseases classified elsewhere [Sibling]
  • B96.20 — Unspecified Escherichia coli [E. coli] as the cause of diseases classified elsewhere [Sibling]
  • B96.21 — Shiga toxin-producing Escherichia coli [E. coli] [STEC] O157 as the cause of diseases classified elsewhere [Sibling]
  • B96.23 — Unspecified Shiga toxin-producing Escherichia coli [E. coli] [STEC] as the cause of diseases classified elsewhere [Sibling]
  • B96.29 — Other Escherichia coli [E. coli] as the cause of diseases classified elsewhere [Sibling]
  • and 10 more

Change history (2)

  • FY2020 — Description revised [Change history]
  • and 1 more

Referenced by Other Codes

Clinical classification (AHRQ CCSR):INF003 — Bacterial infections.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.

Named in the grouper logic of 3 MS-DRGs: DRG 867 (MDC 18), DRG 868 (MDC 18), DRG 869 (MDC 18).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name B96.22 or its code family.

10 Use Additional Code instructions across 6 chapters: D59.31 (via B96.2.-), G00.8 (via B96.-), J95.851 (via B96.-), K95.01 (via B96.-), K95.81 (via B96.-), M71.0 (via B96.-), M71.1 (via B96.-), M72.6 (via B96.-), M72.8 (via B96.-), O23 (via B96.-).

Nearest Codes in This Family

Official ICD-10-CM classifications closest to B96.22 in its code family, with their registry titles.

  • B96.0 — Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified elsewhere
  • B96.1 — Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified elsewhere
  • B96.2 — Escherichia coli [E. coli ] as the cause of diseases classified elsewhere
  • B96.20 — Unspecified Escherichia coli [E. coli] as the cause of diseases classified elsewhere
  • B96.21 — Shiga toxin-producing Escherichia coli [E. coli] [STEC] O157 as the cause of diseases classified elsewhere
  • B96.23 — Unspecified Shiga toxin-producing Escherichia coli [E. coli] [STEC] as the cause of diseases classified elsewhere
  • B96.29 — Other Escherichia coli [E. coli] as the cause of diseases classified elsewhere
  • B96.3 — Hemophilus influenzae [H. influenzae] as the cause of diseases classified elsewhere
  • B96.4 — Proteus (mirabilis) (morganii) as the cause of diseases classified elsewhere
  • B96.5 — Pseudomonas (aeruginosa) (mallei) (pseudomallei) as the cause of diseases classified elsewhere

View all codes in the B96 family

Indexed Clinical Terms (2)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Escherichia coli, as cause of disease classified elsewhere (E. coli), non-O157 Shiga toxin-producing (with known O group)
  • Escherichia coli, as cause of disease classified elsewhere (E. coli), O157:H7 with or without confirmation of Shiga toxin-production, specified NEC