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ICD-10/C05.1

C05.1 ICD-10-CM Code: Malignant neoplasm of soft palate

C05.1 is the authoritative medical code for Malignant neoplasm of soft palate. This classification is used in medical billing and clinical recording to specify the clinical criteria for malignant neoplasm of soft palate (ICD-10-CM C05.1), ensuring healthcare documentation aligns with current federal coding standards.

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 011 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITH MCC (MDC PRE)
  • MS-DRG 012 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITH CC (MDC PRE)
  • MS-DRG 013 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITHOUT CC/MCC (MDC PRE)
  • MS-DRG 146 — EAR, NOSE, MOUTH AND THROAT MALIGNANCY WITH MCC (MDC 03)
  • MS-DRG 147 — EAR, NOSE, MOUTH AND THROAT MALIGNANCY WITH CC (MDC 03)
  • MS-DRG 148 — EAR, NOSE, MOUTH AND THROAT MALIGNANCY WITHOUT CC/MCC (MDC 03)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Malignant neoplasm of soft palate is a billable ICD-10-CM diagnosis code (C05.1). Excludes1 (not coded here): Kaposi's sarcoma of palate (C46.2). Excludes2 (not included here): malignant neoplasm of nasopharyngeal surface of soft palate (C11.3). Use additional code: code to identify:; alcohol abuse and dependence (F10.-); history of tobacco dependence (Z87.891); tobacco dependence (F17.-); tobacco use (Z72.0).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for C05.1 in the official ICD-10-CM tabular list.

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • Kaposi's sarcoma of palate (C46.2)

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • malignant neoplasm of nasopharyngeal surface of soft palate (C11.3)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code to identify:
  • alcohol abuse and dependence (F10.-)
  • history of tobacco dependence (Z87.891)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Frequently Asked Questions (FAQ) & Clinical Guidance

What can't be coded together with C05.1?

Per official ICD-10-CM Excludes1 instructions, C05.1 must not be reported together with: Kaposi's sarcoma of palate (C46.2).

Can C05.1 be reported alongside related conditions?

Per official ICD-10-CM Excludes2 instructions, C05.1 and the following are not considered part of each other and may both be reported when both conditions are present: malignant neoplasm of nasopharyngeal surface of soft palate (C11.3).

Is an additional code needed with C05.1?

Use additional code(s) to specify: code to identify:; alcohol abuse and dependence (F10.-); history of tobacco dependence (Z87.891); tobacco dependence (F17.-).

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C05.1 in its code family, with their registry titles.

  • C05 — Malignant neoplasm of palate
  • C05.0 — Malignant neoplasm of hard palate
  • C05.2 — Malignant neoplasm of uvula
  • C05.8 — Malignant neoplasm of overlapping sites of palate
  • C05.9 — Malignant neoplasm of palate, unspecified

View all codes in the C05 family

Neoplasm Table Sites (1)

Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.

  • Neoplasm, neoplastic, palate, soft — Malignant, Primary