C51.0 ICD-10-CM Code: Malignant neoplasm of labium majus
C51.0 is the authoritative medical code for Malignant neoplasm of labium majus. This classification is used in medical billing and clinical recording to specify the clinical criteria for malignant neoplasm of labium majus (ICD-10-CM C51.0), ensuring healthcare documentation aligns with current federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Inpatient Payment Groups (MS-DRG)
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.
- MS-DRG 736 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITH MCC (MDC 13)
- MS-DRG 737 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITH CC (MDC 13)
- MS-DRG 738 — UTERINE AND ADNEXA PROCEDURES FOR OVARIAN OR ADNEXAL MALIGNANCY WITHOUT CC/MCC (MDC 13)
- MS-DRG 739 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITH MCC (MDC 13)
- MS-DRG 740 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITH CC (MDC 13)
- MS-DRG 741 — UTERINE AND ADNEXA PROCEDURES FOR NON-OVARIAN AND NON-ADNEXAL MALIGNANCY WITHOUT CC/MCC (MDC 13)
- MS-DRG 754 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITH MCC (MDC 13)
- MS-DRG 755 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITH CC (MDC 13)
- MS-DRG 756 — MALIGNANCY, FEMALE REPRODUCTIVE SYSTEM WITHOUT CC/MCC (MDC 13)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.
Official Registry Overview & Definition
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for C51.0 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- malignant neoplasm of skin of female genital organs
Inclusion Terms
Alternative terms the tabular list files under this code.
- Malignant neoplasm of Bartholin's [greater vestibular] gland
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- carcinoma in situ of vulva (D07.1)
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with C51.0?
Per official ICD-10-CM Excludes1 instructions, C51.0 must not be reported together with: carcinoma in situ of vulva (D07.1).
What conditions are included under C51.0?
Malignant neoplasm of labium majus includes: Malignant neoplasm of Bartholin's [greater vestibular] gland.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to C51.0 in its code family, with their registry titles.
Indexed Clinical Terms (1)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Melanoma (malignant), skin, labium, majus
Neoplasm Table Sites (7)
Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.
- Neoplasm, neoplastic, Bartholin's gland — Malignant, Primary
- Neoplasm, neoplastic, labia (skin), majora — Malignant, Primary
- Neoplasm, neoplastic, labium (skin), majus — Malignant, Primary
- Neoplasm, neoplastic, skin NOS, female genital organs (external), labium NEC, majus — Malignant, Primary
- Neoplasm, neoplastic, skin NOS, labia, majora — Malignant, Primary
- Neoplasm, neoplastic, vestibular gland, greater — Malignant, Primary
- Neoplasm, neoplastic, vulvovaginal gland — Malignant, Primary