C81.22 is the authoritative medical code for Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes. This classification is used in medical billing and clinical recording to specify the clinical criteria for mixed cellularity hodgkin lymphoma, intrathoracic lymph nodes (ICD-10-CM C81.22), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes is a billable ICD-10-CM diagnosis code C81.22. Excludes1 (not coded here): personal history of Hodgkin lymphoma Z85.71. Excludes2 (not included here): Kaposi's sarcoma of lymph nodes C46.3; secondary and unspecified neoplasm of lymph nodes C77.-; secondary neoplasm of bone marrow C79.52; secondary neoplasm of spleen C78.89.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for C81.22 in the official ICD-10-CM tabular list.
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- personal history of Hodgkin lymphoma Z85.71
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Kaposi's sarcoma of lymph nodes C46.3
- secondary and unspecified neoplasm of lymph nodes C77.-
- secondary neoplasm of bone marrow C79.52
- secondary neoplasm of spleen C78.89
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with C81.22?
Per official ICD-10-CM Excludes1 instructions, C81.22 must not be reported together with: personal history of Hodgkin lymphoma (Z85.71).
Can C81.22 be reported alongside related conditions?
Per official ICD-10-CM Excludes2 instructions, C81.22 and the following are not considered part of each other and may both be reported when both conditions are present: Kaposi's sarcoma of lymph nodes (C46.3); secondary and unspecified neoplasm of lymph nodes (C77.-); secondary neoplasm of bone marrow (C79.52); secondary neoplasm of spleen (C78.89).
Nearest Codes in This Family
Official ICD-10-CM classifications closest to C81.22 in its code family, with their registry titles.
- C81 — Hodgkin lymphoma
- C81-C96 — Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
- C81.0 — Nodular lymphocyte predominant Hodgkin lymphoma
- C81.00 — Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site
- C81.01 — Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.02 — Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes
- C81.03 — Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.04 — Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.05 — Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.06 — Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes
View all 40 codes in the C81 family