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ICD-10/C82.51

C82.51 ICD-10-CM Code: Diffuse follicle center lymphoma, lymph nodes of head, face, and neck

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B. Showing 12 of 15.

  • MS-DRG 011 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITH MCC (MDC PRE)
  • MS-DRG 012 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITH CC (MDC PRE)
  • MS-DRG 013 — TRACHEOSTOMY FOR FACE, MOUTH AND NECK DIAGNOSES OR LARYNGECTOMY WITHOUT CC/MCC (MDC PRE)
  • MS-DRG 820 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC (MDC 17)
  • MS-DRG 821 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC (MDC 17)
  • MS-DRG 822 — LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 823 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH MCC (MDC 17)
  • MS-DRG 824 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITH CC (MDC 17)
  • MS-DRG 825 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH OTHER PROCEDURES WITHOUT CC/MCC (MDC 17)
  • MS-DRG 840 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH MCC (MDC 17)
  • MS-DRG 841 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITH CC (MDC 17)
  • MS-DRG 842 — LYMPHOMA AND NON-ACUTE LEUKEMIA WITHOUT CC/MCC (MDC 17)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 21 — Lymphoma and Other Cancers (supersedes HCC 22, HCC 23)

Other models: CMS-HCC V22 HCC 10 · RxHCC V08 HCC 21

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Diffuse follicle center lymphoma, lymph nodes of head, face, and neck is a billable ICD-10-CM diagnosis code (C82.51).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for C82.51 in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • follicular lymphoma with or without diffuse areas

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • mature T/NK-cell lymphomas (C84.-)
  • personal history of non-Hodgkin lymphoma (Z85.72)

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C82.51 in its code family, with their registry titles.

  • C82.48 — Follicular lymphoma grade IIIb, lymph nodes of multiple sites
  • C82.49 — Follicular lymphoma grade IIIb, extranodal and solid organ sites
  • C82.4A — Follicular lymphoma grade IIIb, in remission
  • C82.5 — Diffuse follicle center lymphoma
  • C82.50 — Diffuse follicle center lymphoma, unspecified site
  • C82.52 — Diffuse follicle center lymphoma, intrathoracic lymph nodes
  • C82.53 — Diffuse follicle center lymphoma, intra-abdominal lymph nodes
  • C82.54 — Diffuse follicle center lymphoma, lymph nodes of axilla and upper limb
  • C82.55 — Diffuse follicle center lymphoma, lymph nodes of inguinal region and lower limb
  • C82.56 — Diffuse follicle center lymphoma, intrapelvic lymph nodes

View all codes in the C82 family