D48.1 is the authoritative medical code for Neoplasm of uncertain behavior of connective and other soft tissue. This classification is used in medical billing and clinical recording to specify the clinical criteria for neoplasm of uncertain behavior of connective and other soft tissue (ICD-10-CM D48.1), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Official Registry Overview & Definition
Neoplasm of uncertain behavior of connective and other soft tissue is a non-billable ICD-10-CM category code D48.1. A more specific billable subcode must be selected for claims submission. Inclusion terms: Neoplasm of uncertain behavior of connective tissue of ear; Neoplasm of uncertain behavior of connective tissue of eyelid; Stromal tumors of uncertain behavior of digestive system. Excludes1 (not coded here): neoplasm of uncertain behavior of articular cartilage D48.0; neoplasm of uncertain behavior of cartilage of larynx D38.0; neoplasm of uncertain behavior of cartilage of nose D38.5; neoplasm of uncertain behavior of connective tissue of breast D48.6-; neurofibromatosis nonmalignant Q85.0-; neoplasms of unspecified behavior D49.-.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for D48.1 in the official ICD-10-CM tabular list.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Neoplasm of uncertain behavior of connective tissue of ear
- Neoplasm of uncertain behavior of connective tissue of eyelid
- Stromal tumors of uncertain behavior of digestive system
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- neoplasm of uncertain behavior of articular cartilage D48.0
- neoplasm of uncertain behavior of cartilage of larynx D38.0
- neoplasm of uncertain behavior of cartilage of nose D38.5
- neoplasm of uncertain behavior of connective tissue of breast D48.6-
- neurofibromatosis nonmalignant Q85.0-
- neoplasms of unspecified behavior D49.-
Frequently Asked Questions (FAQ) & Clinical Guidance
Can D48.1 be billed directly?
No. D48.1 (Neoplasm of uncertain behavior of connective and other soft tissue) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
What can't be coded together with D48.1?
Per Excludes1 instructions, D48.1 must not be reported with: neoplasm of uncertain behavior of articular cartilage (D48.0); neoplasm of uncertain behavior of cartilage of larynx (D38.0); neoplasm of uncertain behavior of cartilage of nose (D38.5); neoplasm of uncertain behavior of connective tissue of breast (D48.6-).
What conditions are included under D48.1?
Neoplasm of uncertain behavior of connective and other soft tissue includes: Neoplasm of uncertain behavior of connective tissue of ear; Neoplasm of uncertain behavior of connective tissue of eyelid; Stromal tumors of uncertain behavior of digestive system.
Codes in This Family (24)
Official ICD-10-CM classifications in the same code family as D48.1, with their registry titles.
- D48 — Neoplasm of uncertain behavior of other and unspecified sites
- D48.0 — Neoplasm of uncertain behavior of bone and articular cartilage
- D48.11 — Desmoid tumor
- D48.110 — Desmoid tumor of head and neck
- D48.111 — Desmoid tumor of chest wall
- D48.112 — Desmoid tumor, intrathoracic
- D48.113 — Desmoid tumor of abdominal wall
- D48.114 — Desmoid tumor, intraabdominal
- D48.115 — Desmoid tumor of upper extremity and shoulder girdle
- D48.116 — Desmoid tumor of lower extremity and pelvic girdle
- D48.117 — Desmoid tumor of back
- D48.118 — Desmoid tumor of other site
- D48.119 — Desmoid tumor of unspecified site
- D48.19 — Other specified neoplasm of uncertain behavior of connective and other soft tissue
- D48.2 — Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
- D48.3 — Neoplasm of uncertain behavior of retroperitoneum
- D48.4 — Neoplasm of uncertain behavior of peritoneum
- D48.5 — Neoplasm of uncertain behavior of skin
- D48.6 — Neoplasm of uncertain behavior of breast
- D48.60 — Neoplasm of uncertain behavior of unspecified breast
- D48.61 — Neoplasm of uncertain behavior of right breast
- D48.62 — Neoplasm of uncertain behavior of left breast
- D48.7 — Neoplasm of uncertain behavior of other specified sites
- D48.9 — Neoplasm of uncertain behavior, unspecified
Neoplasm Table Sites (113)
Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.
- Neoplasm, neoplastic, abdomen, abdominal, wall, connective tissue — Uncertain Behavior
- Neoplasm, neoplastic, adipose tissue — Uncertain Behavior
- Neoplasm, neoplastic, aorta (thoracic) — Uncertain Behavior
- Neoplasm, neoplastic, aorta (thoracic), abdominal — Uncertain Behavior
- Neoplasm, neoplastic, aponeurosis — Uncertain Behavior
- Neoplasm, neoplastic, aponeurosis, palmar — Uncertain Behavior
- Neoplasm, neoplastic, aponeurosis, plantar — Uncertain Behavior
- Neoplasm, neoplastic, carotid (artery) — Uncertain Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), auricular — Uncertain Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), ear (external) — Uncertain Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), eyelid — Uncertain Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), pinna — Uncertain Behavior
- Neoplasm, neoplastic, coccygeal, body or glomus — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, abdomen — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, abdominal wall — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, ankle — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, antecubital fossa or space — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, arm — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, auricle (ear) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, axilla — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, back — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, buttock — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, calf — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, cervical region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, cheek — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, chest (wall) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, chin — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, diaphragm — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, ear (external) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, elbow — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, extrarectal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity, lower — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity, upper — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, eyelid — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, face — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, finger — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, flank — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, foot — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, forearm — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, forehead — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, gastric — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, gastrointestinal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, gluteal region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, great vessels NEC — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, groin — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, hand — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, head — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, heel — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, hip — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, hypochondrium — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, iliopsoas muscle — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, infraclavicular region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, inguinal (canal) (region) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, intestinal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, intrathoracic — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, ischiorectal fossa — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, jaw — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, knee — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, leg — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC, lower — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC, upper — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, nates — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, neck — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, orbit — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, para-urethral — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, pararectal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, paravaginal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, pelvis (floor) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, pelvo-abdominal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, perineum — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, perirectal (tissue) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, periurethral (tissue) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, popliteal fossa or space — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, presacral — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, psoas muscle — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, pterygoid fossa — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, rectovaginal septum or wall — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, rectovesical — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, sacrococcygeal region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, scalp — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, scapular region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, shoulder — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, stomach — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, submental — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, supraclavicular region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, temple — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, temporal region — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, thigh — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, thoracic (duct) (wall) — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, thorax — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, thumb — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, toe — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, trunk — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, umbilicus — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, vesicorectal — Uncertain Behavior
- Neoplasm, neoplastic, connective tissue NEC, wrist — Uncertain Behavior
- Neoplasm, neoplastic, diaphragm — Uncertain Behavior
- Neoplasm, neoplastic, ear (external), cartilage — Uncertain Behavior
- Neoplasm, neoplastic, eyelid (lower) (skin) (upper), cartilage — Uncertain Behavior
- Neoplasm, neoplastic, fascia, palmar — Uncertain Behavior
- Neoplasm, neoplastic, fascia, plantar — Uncertain Behavior
- Neoplasm, neoplastic, fossa (of), pterygoid — Uncertain Behavior
- Neoplasm, neoplastic, glomus, coccygeal — Uncertain Behavior
- Neoplasm, neoplastic, great vessels NEC — Uncertain Behavior
- Neoplasm, neoplastic, lymph, lymphatic channel NEC — Uncertain Behavior
- Neoplasm, neoplastic, lymph, lymphatic channel NEC, vessel — Uncertain Behavior
- Neoplasm, neoplastic, pterygoid fossa — Uncertain Behavior
- Neoplasm, neoplastic, thorax, thoracic (cavity) (organs NEC), duct — Uncertain Behavior
- Neoplasm, neoplastic, vena cava (abdominal) (inferior) — Uncertain Behavior
- Neoplasm, neoplastic, vena cava (abdominal) (inferior), superior — Uncertain Behavior
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:
ICD Code D43.1
Neoplasm of uncertain behavior of brain, infratentorial
ICD Code D51.1
Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria