D49.2 is the authoritative medical code for Neoplasm of unspecified behavior of bone, soft tissue, and skin. This classification is used in medical billing and clinical recording to specify the clinical criteria for neoplasm of unspecified behavior of bone, soft tissue, and skin (ICD-10-CM D49.2), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Neoplasm of unspecified behavior of bone, soft tissue, and skin is a billable ICD-10-CM diagnosis code D49.2. Includes: 'growth' NOS; neoplasm NOS; new growth NOS; tumor NOS. Excludes1 (not coded here): neoplasm of unspecified behavior of anal canal D49.0; neoplasm of unspecified behavior of anus NOS D49.0; neoplasm of unspecified behavior of bone marrow D49.89; neoplasm of unspecified behavior of cartilage of larynx D49.1; neoplasm of unspecified behavior of cartilage of nose D49.1; neoplasm of unspecified behavior of connective tissue of breast D49.3; neoplasm of unspecified behavior of skin of genital organs D49.59; neoplasm of unspecified behavior of vermilion border of lip D49.0. Excludes2 (not included here): neoplasms of uncertain behavior (D37-D44, D48).
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for D49.2 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- 'growth' NOS
- neoplasm NOS
- new growth NOS
- tumor NOS
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- neoplasm of unspecified behavior of anal canal D49.0
- neoplasm of unspecified behavior of anus NOS D49.0
- neoplasm of unspecified behavior of bone marrow D49.89
- neoplasm of unspecified behavior of cartilage of larynx D49.1
- neoplasm of unspecified behavior of cartilage of nose D49.1
- neoplasm of unspecified behavior of connective tissue of breast D49.3
- neoplasm of unspecified behavior of skin of genital organs D49.59
- neoplasm of unspecified behavior of vermilion border of lip D49.0
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- neoplasms of uncertain behavior (D37-D44, D48)
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with D49.2?
Per Excludes1 instructions, D49.2 must not be reported with: neoplasm of unspecified behavior of anal canal (D49.0); neoplasm of unspecified behavior of anus NOS (D49.0); neoplasm of unspecified behavior of bone marrow (D49.89); neoplasm of unspecified behavior of cartilage of larynx (D49.1).
Can D49.2 be reported alongside related conditions?
Per Excludes2 instructions, D49.2 and the following may both be reported when both are present: neoplasms of uncertain behavior (D37-D44, D48).
Codes in This Family (17)
Official ICD-10-CM classifications in the same code family as D49.2, with their registry titles.
- D49 — Neoplasms of unspecified behavior
- D49.0 — Neoplasm of unspecified behavior of digestive system
- D49.1 — Neoplasm of unspecified behavior of respiratory system
- D49.3 — Neoplasm of unspecified behavior of breast
- D49.4 — Neoplasm of unspecified behavior of bladder
- D49.5 — Neoplasm of unspecified behavior of other genitourinary organs
- D49.51 — Neoplasm of unspecified behavior of kidney
- D49.511 — Neoplasm of unspecified behavior of right kidney
- D49.512 — Neoplasm of unspecified behavior of left kidney
- D49.519 — Neoplasm of unspecified behavior of unspecified kidney
- D49.59 — Neoplasm of unspecified behavior of other genitourinary organ
- D49.6 — Neoplasm of unspecified behavior of brain
- D49.7 — Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
- D49.8 — Neoplasm of unspecified behavior of other specified sites
- D49.81 — Neoplasm of unspecified behavior of retina and choroid
- D49.89 — Neoplasm of unspecified behavior of other specified sites
- D49.9 — Neoplasm of unspecified behavior of unspecified site
Indexed Clinical Terms (20)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Osteitis, deformans, in (due to), neoplastic disease, carpus
- Osteitis, deformans, in (due to), neoplastic disease, clavicle
- Osteitis, deformans, in (due to), neoplastic disease, femur
- Osteitis, deformans, in (due to), neoplastic disease, fibula
- Osteitis, deformans, in (due to), neoplastic disease, finger
- Osteitis, deformans, in (due to), neoplastic disease, humerus
- Osteitis, deformans, in (due to), neoplastic disease, ilium
- Osteitis, deformans, in (due to), neoplastic disease, ischium
- Osteitis, deformans, in (due to), neoplastic disease, metacarpus
- Osteitis, deformans, in (due to), neoplastic disease, metatarsus
- Osteitis, deformans, in (due to), neoplastic disease, neck
- Osteitis, deformans, in (due to), neoplastic disease, radius
- Osteitis, deformans, in (due to), neoplastic disease, rib
- Osteitis, deformans, in (due to), neoplastic disease, scapula
- Osteitis, deformans, in (due to), neoplastic disease, skull
- Osteitis, deformans, in (due to), neoplastic disease, tarsus
- Osteitis, deformans, in (due to), neoplastic disease, tibia
- Osteitis, deformans, in (due to), neoplastic disease, toe
- Osteitis, deformans, in (due to), neoplastic disease, ulna
- Osteitis, deformans, in (due to), neoplastic disease, vertebra
Neoplasm Table Sites (200)
Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.
- Neoplasm, neoplastic, abdomen, abdominal, wall — Unspecified Behavior
- Neoplasm, neoplastic, abdomen, abdominal, wall, connective tissue — Unspecified Behavior
- Neoplasm, neoplastic, adipose tissue — Unspecified Behavior
- Neoplasm, neoplastic, ala nasi (external) — Unspecified Behavior
- Neoplasm, neoplastic, alveolar, ridge or process — Unspecified Behavior
- Neoplasm, neoplastic, alveolar, ridge or process, lower — Unspecified Behavior
- Neoplasm, neoplastic, alveolar, ridge or process, upper — Unspecified Behavior
- Neoplasm, neoplastic, anus, anal, margin — Unspecified Behavior
- Neoplasm, neoplastic, anus, anal, skin — Unspecified Behavior
- Neoplasm, neoplastic, aorta (thoracic) — Unspecified Behavior
- Neoplasm, neoplastic, aorta (thoracic), abdominal — Unspecified Behavior
- Neoplasm, neoplastic, aponeurosis — Unspecified Behavior
- Neoplasm, neoplastic, aponeurosis, palmar — Unspecified Behavior
- Neoplasm, neoplastic, aponeurosis, plantar — Unspecified Behavior
- Neoplasm, neoplastic, atlas — Unspecified Behavior
- Neoplasm, neoplastic, auditory, canal (external) (skin) — Unspecified Behavior
- Neoplasm, neoplastic, auricle, ear — Unspecified Behavior
- Neoplasm, neoplastic, auricular canal (external) — Unspecified Behavior
- Neoplasm, neoplastic, auricular canal (external), internal — Unspecified Behavior
- Neoplasm, neoplastic, axilla, axillary, fold — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), acetabulum — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), atlas — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), axis — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), back NEC — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), calvarium — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), cartilage NEC — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), clavicle — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), clivus — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), coccygeal vertebra — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), coccyx — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), costal cartilage — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), costovertebral joint — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), cranial — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), cuneiform — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), ethmoid (labyrinth) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), face — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), frontal — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), hip — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), hyoid — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), ilium — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), innominate — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), intervertebral cartilage or disc — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), ischium — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), jaw (lower) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), malar — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), mandible — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), mastoid — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), maxilla, maxillary (superior) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), maxilla, maxillary (superior), inferior — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), nose, nasal — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), occipital — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), orbit — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), parietal — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), pelvic — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), pubic — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), rib — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), sacral vertebra — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), sacrum — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), sella turcica — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), skull — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), sphenoid — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), spine, spinal (column) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), spine, spinal (column), coccyx — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), spine, spinal (column), sacrum — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), sternum — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), temporal — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), turbinate — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), vertebra (column) — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), vertebra (column), coccyx — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), vertebra (column), sacrum — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), vomer — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), xiphoid process — Unspecified Behavior
- Neoplasm, neoplastic, bone (periosteum), zygomatic — Unspecified Behavior
- Neoplasm, neoplastic, brachial plexus — Unspecified Behavior
- Neoplasm, neoplastic, breast (connective tissue) (glandular tissue) (soft parts), skin — Unspecified Behavior
- Neoplasm, neoplastic, brow — Unspecified Behavior
- Neoplasm, neoplastic, calvarium — Unspecified Behavior
- Neoplasm, neoplastic, canal, auditory (external) — Unspecified Behavior
- Neoplasm, neoplastic, canal, auricular (external) — Unspecified Behavior
- Neoplasm, neoplastic, canthus (eye) (inner) (outer) — Unspecified Behavior
- Neoplasm, neoplastic, carotid (artery) — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint) — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), auricular — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), costal — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), ear (external) — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), ensiform — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), eyelid — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), intervertebral — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), pinna — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), rib — Unspecified Behavior
- Neoplasm, neoplastic, cartilage NEC (articular) (joint), semilunar (knee) — Unspecified Behavior
- Neoplasm, neoplastic, cheek, external — Unspecified Behavior
- Neoplasm, neoplastic, chin — Unspecified Behavior
- Neoplasm, neoplastic, clavicle — Unspecified Behavior
- Neoplasm, neoplastic, clivus — Unspecified Behavior
- Neoplasm, neoplastic, coccygeal, body or glomus — Unspecified Behavior
- Neoplasm, neoplastic, coccygeal, vertebra — Unspecified Behavior
- Neoplasm, neoplastic, coccyx — Unspecified Behavior
- Neoplasm, neoplastic, columnella — Unspecified Behavior
- Neoplasm, neoplastic, concha — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, abdomen — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, abdominal wall — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, ankle — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, antecubital fossa or space — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, arm — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, auricle (ear) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, axilla — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, back — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, buttock — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, calf — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, cervical region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, cheek — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, chest (wall) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, chin — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, diaphragm — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, ear (external) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, elbow — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, extrarectal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity, lower — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, extremity, upper — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, eyelid — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, face — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, finger — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, flank — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, foot — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, forearm — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, forehead — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, gastric — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, gastrointestinal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, gluteal region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, great vessels NEC — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, groin — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, hand — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, head — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, heel — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, hip — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, hypochondrium — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, iliopsoas muscle — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, infraclavicular region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, inguinal (canal) (region) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, intestinal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, intrathoracic — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, ischiorectal fossa — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, knee — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, leg — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC, lower — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, limb NEC, upper — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, nates — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, neck — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, para-urethral — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, pararectal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, paravaginal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, pelvis (floor) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, pelvo-abdominal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, perineum — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, perirectal (tissue) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, periurethral (tissue) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, popliteal fossa or space — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, presacral — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, psoas muscle — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, pterygoid fossa — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, rectovaginal septum or wall — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, rectovesical — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, sacrococcygeal region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, scalp — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, scapular region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, shoulder — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, skin NEC (dermis) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, stomach — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, submental — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, supraclavicular region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, temple — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, temporal region — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, thigh — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, thoracic (duct) (wall) — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, thorax — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, thumb — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, toe — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, trunk — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, umbilicus — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, vesicorectal — Unspecified Behavior
- Neoplasm, neoplastic, connective tissue NEC, wrist — Unspecified Behavior
- Neoplasm, neoplastic, costal cartilage — Unspecified Behavior
- Neoplasm, neoplastic, costovertebral joint — Unspecified Behavior
- Neoplasm, neoplastic, diaphragm — Unspecified Behavior
- Neoplasm, neoplastic, disc, intervertebral — Unspecified Behavior
- Neoplasm, neoplastic, ear (external) — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), auricle or auris — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), canal, external — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), cartilage — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), external meatus — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), lobule — Unspecified Behavior
- Neoplasm, neoplastic, ear (external), skin — Unspecified Behavior
- Neoplasm, neoplastic, earlobe — Unspecified Behavior
- Neoplasm, neoplastic, ensiform cartilage — Unspecified Behavior
- Neoplasm, neoplastic, ethmoid (sinus), bone or labyrinth — Unspecified Behavior
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:
ICD Code D48.2
Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system