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ICD-10/D78.21

D78.21 ICD-10-CM Code: Postprocedural hemorrhage of the spleen following a procedure on the spleen

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 919 — COMPLICATIONS OF TREATMENT WITH MCC (MDC 21)
  • MS-DRG 920 — COMPLICATIONS OF TREATMENT WITH CC (MDC 21)
  • MS-DRG 921 — COMPLICATIONS OF TREATMENT WITHOUT CC/MCC (MDC 21)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Postprocedural hemorrhage of the spleen following a procedure on the spleen is a billable ICD-10-CM diagnosis code (D78.21).

Change history

  • FY2017 — 2016-10-01
    Description revised
    Postprocedural hemorrhage and hematoma of the spleen following a procedure on the spleen → Postprocedural hemorrhage of the spleen following a procedure on the spleen
    FY2017 changes
  • FY2017 — 2016-10-01
    Short description revised
    Postprocedural hemor/hemtom of the spleen fol proc on spleen → Postprocedural hemorrhage of the spleen fol proc on spleen
    FY2017 changes

Verify Before Coding

  • Billable — reportable as written.
  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of D78.21 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89) [Hierarchy]

Referenced by Excludes2 notes (10)

  • T80 — Complications following infusion, transfusion and therapeutic injection [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T81 — Complications of procedures, not elsewhere classified [Excludes2](via D78.-): “intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)” · check together
  • T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T83 — Complications of genitourinary prosthetic devices, implants and grafts [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T84 — Complications of internal orthopedic prosthetic devices, implants and grafts [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T85 — Complications of other internal prosthetic devices, implants and grafts [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • T86 — Complications of transplanted organs and tissue [Excludes2](via D78.-): “intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)” · check together
  • and 2 more

Clinical classification (CCSR)

  • BLD009 — Postprocedural or postoperative complications of the spleen [CCSR]

Potential MS-DRG

  • CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”
  • DRG 919 — COMPLICATIONS OF TREATMENT WITH MCC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITH MCC (MDC 21)”
  • DRG 920 — COMPLICATIONS OF TREATMENT WITH CC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITH CC (MDC 21)”
  • DRG 921 — COMPLICATIONS OF TREATMENT WITHOUT CC/MCC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITHOUT CC/MCC (MDC 21)”

MDC crossing · procedures (32029)

  • MDC 21 — Injuries, Poisonings and Toxic Effects of Drugs [MDC crossing]: “Injuries, Poisonings and Toxic Effects of Drugs — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • 0016070 — Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Nasopharynx with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
  • 0016071 — Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Mastoid Sinus with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
  • 0016072 — Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Atrium with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
  • 0016073 — Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Blood Vessel with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
  • 0016074 — Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach [Same-MDC procedure]: “Bypass Cerebral Ventricle to Pleural Cavity with Autologous Tissue Substitute, Open Approach — grouped in MDC 21, the procedure side of this code's crossing.” · check together
  • and 32024 more

Index entries

  • Complication (s) (from) (of), postprocedural, hemorrhage (of), spleen, following procedure on the spleen[Index term]

Nearest codes (17)

  • D78 — Intraoperative and postprocedural complications of the spleen [Sibling]
  • D78.0 — Intraoperative hemorrhage and hematoma of the spleen complicating a procedure [Sibling]
  • D78.01 — Intraoperative hemorrhage and hematoma of the spleen complicating a procedure on the spleen [Sibling]
  • D78.02 — Intraoperative hemorrhage and hematoma of the spleen complicating other procedure [Sibling]
  • D78.1 — Accidental puncture and laceration of the spleen during a procedure [Sibling]
  • D78.11 — Accidental puncture and laceration of the spleen during a procedure on the spleen [Sibling]
  • D78.12 — Accidental puncture and laceration of the spleen during other procedure [Sibling]
  • D78.2 — Postprocedural hemorrhage of the spleen following a procedure [Sibling]
  • and 9 more

Change history (2)

  • FY2017 — Description revised [Change history]
  • and 1 more

Referenced by Other Codes

Clinical classification (AHRQ CCSR):BLD009 — Postprocedural or postoperative complications of the spleen (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 78 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 919 (MDC 21), DRG 920 (MDC 21), DRG 921 (MDC 21).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name D78.21 or its code family.

10 Excludes2 notes: T80 (via D78.-), T80-T88 (via D78.-), T81 (via D78.-), T82 (via D78.-), T83 (via D78.-), T84 (via D78.-), T85 (via D78.-), T86 (via D78.-), T87 (via D78.-), T88 (via D78.-).

Nearest Codes in This Family

Official ICD-10-CM classifications closest to D78.21 in its code family, with their registry titles.

  • D78.02 — Intraoperative hemorrhage and hematoma of the spleen complicating other procedure
  • D78.1 — Accidental puncture and laceration of the spleen during a procedure
  • D78.11 — Accidental puncture and laceration of the spleen during a procedure on the spleen
  • D78.12 — Accidental puncture and laceration of the spleen during other procedure
  • D78.2 — Postprocedural hemorrhage of the spleen following a procedure
  • D78.22 — Postprocedural hemorrhage of the spleen following other procedure
  • D78.3 — Postprocedural hematoma and seroma of the spleen following a procedure
  • D78.31 — Postprocedural hematoma of the spleen following a procedure on the spleen
  • D78.32 — Postprocedural hematoma of the spleen following other procedure
  • D78.33 — Postprocedural seroma of the spleen following a procedure on the spleen

View all codes in the D78 family

Indexed Clinical Terms (1)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Complication (s) (from) (of), postprocedural, hemorrhage (of), spleen, following procedure on the spleen