E72.51 is the authoritative medical code for Non-ketotic hyperglycinemia. This classification is used in medical billing and clinical recording to specify the clinical criteria for non-ketotic hyperglycinemia (ICD-10-CM E72.51), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Official Registry Overview & Definition
Non-ketotic hyperglycinemia is a billable ICD-10-CM diagnosis code E72.51. Excludes1 (not coded here): disorders of:; aromatic amino-acid metabolism E70.-; branched-chain amino-acid metabolism E71.0-E71.2; fatty-acid metabolism E71.3; purine and pyrimidine metabolism E79.-; gout (M1A.-, M10.-); androgen insensitivity syndrome E34.5-; congenital adrenal hyperplasia E25.0; hemolytic anemias attributable to enzyme disorders D55.-; Marfan syndrome Q87.4-; 5-alpha-reductase deficiency E29.1. Excludes2 (not included here): Ehlers-Danlos syndromes Q79.6-.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for E72.51 in the official ICD-10-CM tabular list.
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- disorders of:
- aromatic amino-acid metabolism E70.-
- branched-chain amino-acid metabolism E71.0-E71.2
- fatty-acid metabolism E71.3
- purine and pyrimidine metabolism E79.-
- gout (M1A.-, M10.-)
- androgen insensitivity syndrome E34.5-
- congenital adrenal hyperplasia E25.0
- hemolytic anemias attributable to enzyme disorders D55.-
- Marfan syndrome Q87.4-
- 5-alpha-reductase deficiency E29.1
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- Ehlers-Danlos syndromes Q79.6-
Frequently Asked Questions (FAQ) & Clinical Guidance
What can't be coded together with E72.51?
Per Excludes1 instructions, E72.51 must not be reported with: disorders of:; aromatic amino-acid metabolism (E70.-); branched-chain amino-acid metabolism (E71.0-E71.2); fatty-acid metabolism (E71.3).
Can E72.51 be reported alongside related conditions?
Per Excludes2 instructions, E72.51 and the following may both be reported when both are present: Ehlers-Danlos syndromes (Q79.6-).
Codes in This Family (37)
Official ICD-10-CM classifications in the same code family as E72.51, with their registry titles.
- E72 — Other disorders of amino-acid metabolism
- E72.0 — Disorders of amino-acid transport
- E72.01 — Cystinuria
- E72.02 — Hartnup's disease
- E72.03 — Lowe's syndrome
- E72.04 — Cystinosis
- E72.09 — Other disorders of amino-acid transport
- E72.1 — Disorders of sulfur-bearing amino-acid metabolism
- E72.10 — Disorders of sulfur-bearing amino-acid metabolism, unspecified
- E72.11 — Homocystinuria
- E72.12 — Methylenetetrahydrofolate reductase deficiency
- E72.19 — Other disorders of sulfur-bearing amino-acid metabolism
- E72.2 — Disorders of urea cycle metabolism
- E72.20 — Disorder of urea cycle metabolism, unspecified
- E72.21 — Argininemia
- E72.22 — Arginosuccinic aciduria
- E72.23 — Citrullinemia
- E72.29 — Other disorders of urea cycle metabolism
- E72.3 — Disorders of lysine and hydroxylysine metabolism
- E72.4 — Disorders of ornithine metabolism
- E72.5 — Disorders of glycine metabolism
- E72.50 — Disorder of glycine metabolism, unspecified
- E72.52 — Trimethylaminuria
- E72.53 — Primary hyperoxaluria
- E72.530 — Primary hyperoxaluria, type 1
- E72.538 — Other specified primary hyperoxaluria
- E72.539 — Primary hyperoxaluria, unspecified
- E72.54 — Secondary hyperoxaluria
- E72.540 — Dietary hyperoxaluria
- E72.541 — Enteric hyperoxaluria
- E72.548 — Other secondary hyperoxaluria
- E72.549 — Secondary hyperoxaluria, unspecified
- E72.59 — Other disorders of glycine metabolism
- E72.8 — Other specified disorders of amino-acid metabolism
- E72.81 — Disorders of gamma aminobutyric acid metabolism
- E72.89 — Other specified disorders of amino-acid metabolism
- E72.9 — Disorder of amino-acid metabolism, unspecified
Indexed Clinical Terms (6)
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.
- Disorder (of), glycine metabolism, non-ketotic hyperglycinemia
- Disorder (of), metabolism NOS, amino-acid, glycine, non-ketotic hyperglycinemia
- Glucoglycinuria
- Glycinemia
- Hyperglycinemia (non-ketotic)
- Non-ketotic hyperglycinemia
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures: