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ICD-10/I81

I81 ICD-10-CM Code: Portal vein thrombosis

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 441 — DISORDERS OF LIVER EXCEPT MALIGNANCY, CIRRHOSIS OR ALCOHOLIC HEPATITIS WITH MCC (MDC 07)
  • MS-DRG 442 — DISORDERS OF LIVER EXCEPT MALIGNANCY, CIRRHOSIS OR ALCOHOLIC HEPATITIS WITH CC (MDC 07)
  • MS-DRG 443 — DISORDERS OF LIVER EXCEPT MALIGNANCY, CIRRHOSIS OR ALCOHOLIC HEPATITIS WITHOUT CC/MCC (MDC 07)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Portal vein thrombosis is a billable ICD-10-CM diagnosis code (I81).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for I81 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Portal (vein) obstruction

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • hepatic vein thrombosis (I82.0)
  • phlebitis of portal vein (K75.1)

Indexed Clinical Terms (6)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Block, blocked, portal (vein)
  • Embolism (multiple) (paradoxical), portal (vein)
  • Obstruction, obstructed, obstructive, portal (circulation) (vein)
  • Pseudoangioma
  • Thrombosis, thrombotic (bland) (multiple) (progressive) (silent) (vessel), liver (venous), portal vein
  • Thrombosis, thrombotic (bland) (multiple) (progressive) (silent) (vessel), portal