ICD-10/K21.01

K21.01 ICD 2026 Code: Gastro-esophageal reflux disease with esophagitis, with bleeding

K21.01 is the authoritative medical code for Gastro-esophageal reflux disease with esophagitis, with bleeding. This classification is used in medical billing and clinical recording to specify the clinical criteria for gastro-esophageal reflux disease with esophagitis, with bleeding (ICD-10-CM K21.01), ensuring healthcare documentation aligns with 2026 federal coding standards.

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Official Registry Overview & Definition

Gastro-esophageal reflux disease with esophagitis, with bleeding is a billable ICD-10-CM diagnosis code K21.01. Excludes1 (not coded here): newborn esophageal reflux P78.83. Excludes2 (not included here): hiatus hernia K44.-.

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for K21.01 in the official ICD-10-CM tabular list.

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • newborn esophageal reflux P78.83

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • hiatus hernia K44.-

Frequently Asked Questions (FAQ) & Clinical Guidance

What can't be coded together with K21.01?

Per Excludes1 instructions, K21.01 must not be reported with: newborn esophageal reflux (P78.83).

Can K21.01 be reported alongside related conditions?

Per Excludes2 instructions, K21.01 and the following may both be reported when both are present: hiatus hernia (K44.-).

Codes in This Family (3)

Official ICD-10-CM classifications in the same code family as K21.01, with their registry titles.

  • K21 — Gastro-esophageal reflux disease
  • K21.0 — Gastro-esophageal reflux disease with esophagitis
  • K21.9 — Gastro-esophageal reflux disease without esophagitis

Indexed Clinical Terms (7)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Allergy, allergic (reaction) (to), milk protein, gastroesophageal reflux, with esophagitis (without bleeding), with bleeding
  • Disease, diseased, gastroesophageal reflux (GERD), with esophagitis (without bleeding), with bleeding
  • Esophagitis (acute) (alkaline) (chemical) (chronic) (infectional) (necrotic) (peptic) (postoperative) (without bleeding), due to gastrointestinal reflux disease (without bleeding), with bleeding
  • Esophagitis (acute) (alkaline) (chemical) (chronic) (infectional) (necrotic) (peptic) (postoperative) (without bleeding), reflux, with bleeding
  • Reflux, esophageal, with esophagitis (without bleeding), with bleeding
  • Reflux, gastroesophageal, with esophagitis (without bleeding), with bleeding
  • Ulcer, ulcerated, ulcerating, ulceration, ulcerative, esophagus (peptic), due to, gastrointestinal reflux disease (without bleeding), with bleeding

Related Codes & Numerical Sequence (Crawl Map)

Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:

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