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N42.31 ICD-10-CM Code: Prostatic intraepithelial neoplasia

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 729 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITH CC/MCC (MDC 12)
  • MS-DRG 730 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITHOUT CC/MCC (MDC 12)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Prostatic intraepithelial neoplasia is a billable ICD-10-CM diagnosis code (N42.31).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for N42.31 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • PIN
  • Prostatic intraepithelial neoplasia I (PIN I)
  • Prostatic intraepithelial neoplasia II (PIN II)

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Indexed Clinical Terms (3)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN)
  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN), grade I
  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN), grade II

Frequently Compared Codes

The official Excludes notes on N42.31 name these codes. Each comparison page covers when the two can — or must not — be reported together.

Change history

  • FY2017 — 2016-10-01
    Added to the code set
    Prostatic intraepithelial neoplasia
    FY2017 changes

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Relationships & Classification

Official ICD-10-CM tabular notes on other codes that name N42.31 or its code family.

1 Excludes1 notes: D07.5 (via N42.3.-).

Potential MS-DRG Relationships (FY2026)

Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.

Named in the grouper logic of 2 MS-DRGs: DRG 729 (MDC 12), DRG 730 (MDC 12).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):GEN016 — Other specified male genital disorders (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Contextual Map

Every relationship of N42.31 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • N00-N99 — Chapter 14: Diseases of the Genitourinary System (N00-N99) (N00-N99) [Hierarchy]
  • N40-N53 — Diseases of male genital organs [Hierarchy]

Excludes1

  • D07.5 — Carcinoma in situ of prostate [Excludes1]: “prostatic intraepithelial neoplasia III (PIN III) (D07.5)” · check together

Referenced by Excludes1 notes

  • D07.5 — Carcinoma in situ of prostate [Excludes1](via N42.3.-): “dysplasia (mild) (moderate) of prostate (N42.3-)” · check together

Clinical classification (CCSR)

  • GEN016 — Other specified male genital disorders [CCSR]

Potential MS-DRG

  • DRG 729 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITH CC/MCC [MS-DRG]: “OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITH CC/MCC (MDC 12)”
  • DRG 730 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITHOUT CC/MCC [MS-DRG]: “OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITHOUT CC/MCC (MDC 12)”

MDC crossing · procedures (1964)

  • MDC 12 — Diseases and Disorders of the Male Reproductive System [MDC crossing]: “Diseases and Disorders of the Male Reproductive System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”
  • 00HE0MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Open Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Open Approach — grouped in MDC 12, the procedure side of this code's crossing.” · check together
  • 00HE3MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Approach — grouped in MDC 12, the procedure side of this code's crossing.” · check together
  • 00HE4MZ — Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Endoscopic Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Cranial Nerve, Percutaneous Endoscopic Approach — grouped in MDC 12, the procedure side of this code's crossing.” · check together
  • 00HU0MZ — Insertion of Neurostimulator Lead into Spinal Canal, Open Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Spinal Canal, Open Approach — grouped in MDC 12, the procedure side of this code's crossing.” · check together
  • 00HU3MZ — Insertion of Neurostimulator Lead into Spinal Canal, Percutaneous Approach [Same-MDC procedure]: “Insertion of Neurostimulator Lead into Spinal Canal, Percutaneous Approach — grouped in MDC 12, the procedure side of this code's crossing.” · check together
  • and 1959 more

Index entries

  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN)[Index term]
  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN), grade I[Index term]
  • Neoplasia, intraepithelial (histologically confirmed), prostate (histologically confirmed) (PIN), grade II[Index term]

Nearest codes (13)

  • N42 — Other and unspecified disorders of prostate [Sibling]
  • N42.0 — Calculus of prostate [Sibling]
  • N42.1 — Congestion and hemorrhage of prostate [Sibling]
  • N42.3 — Dysplasia of prostate [Sibling]
  • N42.30 — Unspecified dysplasia of prostate [Sibling]
  • N42.32 — Atypical small acinar proliferation of prostate [Sibling]
  • N42.39 — Other dysplasia of prostate [Sibling]
  • N42.8 — Other specified disorders of prostate [Sibling]
  • and 5 more

Change history

  • FY2017 — Added to the code set [Change history]

Nearest Codes in This Family

Official ICD-10-CM classifications closest to N42.31 in its code family, with their registry titles.

  • N42 — Other and unspecified disorders of prostate
  • N42.0 — Calculus of prostate
  • N42.1 — Congestion and hemorrhage of prostate
  • N42.3 — Dysplasia of prostate
  • N42.30 — Unspecified dysplasia of prostate
  • N42.32 — Atypical small acinar proliferation of prostate
  • N42.39 — Other dysplasia of prostate
  • N42.8 — Other specified disorders of prostate
  • N42.81 — Prostatodynia syndrome
  • N42.82 — Prostatosis syndrome

View all codes in the N42 family