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ICD-10/T46.2

T46.2 ICD-10-CM Code: Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classified

T46.2 is the authoritative medical code for Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classified. This classification is used in medical billing and clinical recording to specify the clinical criteria for poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classified (ICD-10-CM T46.2), ensuring healthcare documentation aligns with current federal coding standards.

Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classified is a non-billable ICD-10-CM category code (T46.2). A more specific billable subcode must be selected for claims submission. Includes: adverse effect of correct substance properly administered; poisoning by overdose of substance; poisoning by wrong substance given or taken in error; underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed. Excludes1 (not coded here): poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists (T44.7-); poisoning by, adverse effect of and underdosing of metaraminol (T44.4); toxic reaction to local anesthesia in pregnancy (O29.3-). Excludes2 (not included here): abuse and dependence of psychoactive substances (F10-F19); abuse of non-dependence-producing substances (F55.-); immunodeficiency due to drugs (D84.821); drug reaction and poisoning affecting newborn (P00-P96); pathological drug intoxication (inebriation) (F10-F19). Code first: , for adverse effects, the nature of the adverse effect, such as:; adverse effect NOS (T88.7); aspirin gastritis (K29.-); blood disorders (D56-D76); contact dermatitis (L23-L25); dermatitis due to substances taken internally (L27.-); nephropathy (N14.0-N14.2). Use additional code: code(s) to specify:; manifestations of poisoning; underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9); underdosing of medication regimen (Z91.12-, Z91.13-). 7th character: The appropriate 7th character is to be added to each code from category T46.

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for T46.2 in the official ICD-10-CM tabular list.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists (T44.7-)
  • poisoning by, adverse effect of and underdosing of metaraminol (T44.4)
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)

Code First

Underlying conditions that must be sequenced before this code.

  • Code first, for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)

Frequently Asked Questions (FAQ) & Clinical Guidance

Can T46.2 be billed directly?

No. T46.2 (Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classified) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.

Does T46.2 require a 7th character?

Yes. The appropriate 7th character is to be added to each code from category T46.

What can't be coded together with T46.2?

Per official ICD-10-CM Excludes1 instructions, T46.2 must not be reported together with: poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists (T44.7-); poisoning by, adverse effect of and underdosing of metaraminol (T44.4); toxic reaction to local anesthesia in pregnancy (O29.3-).

Can T46.2 be reported alongside related conditions?

Per official ICD-10-CM Excludes2 instructions, T46.2 and the following are not considered part of each other and may both be reported when both conditions are present: abuse and dependence of psychoactive substances (F10-F19); abuse of non-dependence-producing substances (F55.-); immunodeficiency due to drugs (D84.821); drug reaction and poisoning affecting newborn (P00-P96).

Does T46.2 need to be sequenced after another code?

Yes. Code first: , for adverse effects, the nature of the adverse effect, such as:; adverse effect NOS (T88.7); aspirin gastritis (K29.-); blood disorders (D56-D76).

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T46.2 in its code family, with their registry titles.

  • T46.1X5S — Adverse effect of calcium-channel blockers, sequela
  • T46.1X6 — Underdosing of calcium-channel blockers
  • T46.1X6A — Underdosing of calcium-channel blockers, initial encounter
  • T46.1X6D — Underdosing of calcium-channel blockers, subsequent encounter
  • T46.1X6S — Underdosing of calcium-channel blockers, sequela
  • T46.2X — Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs
  • T46.2X1 — Poisoning by other antidysrhythmic drugs, accidental (unintentional)
  • T46.2X1A — Poisoning by other antidysrhythmic drugs, accidental (unintentional), initial encounter
  • T46.2X1D — Poisoning by other antidysrhythmic drugs, accidental (unintentional), subsequent encounter
  • T46.2X1S — Poisoning by other antidysrhythmic drugs, accidental (unintentional), sequela

View all codes in the T46 family