T48.2 is the authoritative medical code for Poisoning by, adverse effect of and underdosing of other and unspecified drugs acting on muscles. This classification is used in medical billing and clinical recording to specify the clinical criteria for poisoning by, adverse effect of and underdosing of other and unspecified drugs acting on muscles (ICD-10-CM T48.2), ensuring healthcare documentation aligns with 2026 federal coding standards.
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Official Registry Overview & Definition
Poisoning by, adverse effect of and underdosing of other and unspecified drugs acting on muscles is a non-billable ICD-10-CM category code T48.2. A more specific billable subcode must be selected for claims submission. Includes: adverse effect of correct substance properly administered; poisoning by overdose of substance; poisoning by wrong substance given or taken in error; underdosing by (inadvertently) deliberately taking less substance than prescribed or instructed. Excludes1 (not coded here): toxic reaction to local anesthesia in pregnancy O29.3-. Excludes2 (not included here): abuse and dependence of psychoactive substances F10-F19; abuse of non-dependence-producing substances F55.-; immunodeficiency due to drugs D84.821; drug reaction and poisoning affecting newborn P00-P96; pathological drug intoxication inebriation F10-F19. Code first: , for adverse effects, the nature of the adverse effect, such as:; adverse effect NOS T88.7; aspirin gastritis K29.-; blood disorders D56-D76; contact dermatitis L23-L25; dermatitis due to substances taken internally L27.-; nephropathy N14.0-N14.2. Use additional code: code(s) to specify:; manifestations of poisoning; underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9); underdosing of medication regimen (Z91.12-, Z91.13-). 7th character: The appropriate 7th character is to be added to each code from category T48.
Official Tabular Instructional Notes
Sequencing, inclusion, and exclusion notes published for T48.2 in the official ICD-10-CM tabular list.
Includes
Conditions the official ICD-10-CM tabular list includes under this code.
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) deliberately taking less substance than prescribed or instructed
Excludes1 — Not Coded Here
Conditions that can never be reported with this code; the two are mutually exclusive.
- toxic reaction to local anesthesia in pregnancy O29.3-
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- abuse and dependence of psychoactive substances F10-F19
- abuse of non-dependence-producing substances F55.-
- immunodeficiency due to drugs D84.821
- drug reaction and poisoning affecting newborn P00-P96
- pathological drug intoxication inebriation F10-F19
Code First
Underlying conditions that must be sequenced before this code.
- , for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS T88.7
- aspirin gastritis K29.-
- blood disorders D56-D76
- contact dermatitis L23-L25
- dermatitis due to substances taken internally L27.-
- nephropathy N14.0-N14.2
Use Additional Code
Supplementary codes the tabular list directs you to add.
- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
Frequently Asked Questions (FAQ) & Clinical Guidance
Can T48.2 be billed directly?
No. T48.2 (Poisoning by, adverse effect of and underdosing of other and unspecified drugs acting on muscles) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Does T48.2 require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T48.
What can't be coded together with T48.2?
Per Excludes1 instructions, T48.2 must not be reported with: toxic reaction to local anesthesia in pregnancy (O29.3-).
Can T48.2 be reported alongside related conditions?
Per Excludes2 instructions, T48.2 and the following may both be reported when both are present: abuse and dependence of psychoactive substances (F10-F19); abuse of non-dependence-producing substances (F55.-); immunodeficiency due to drugs (D84.821); drug reaction and poisoning affecting newborn (P00-P96).
Does T48.2 need to be sequenced after another code?
Yes. Code first: , for adverse effects, the nature of the adverse effect, such as:; adverse effect NOS (T88.7); aspirin gastritis (K29.-); blood disorders (D56-D76).
Codes in This Family (40)
Official ICD-10-CM classifications in the same code family as T48.2, with their registry titles.
- T48.201 — Poisoning by unspecified drugs acting on muscles, accidental (unintentional)
- T48.201A — Poisoning by unspecified drugs acting on muscles, accidental (unintentional), initial encounter
- T48.201D — Poisoning by unspecified drugs acting on muscles, accidental (unintentional), subsequent encounter
- T48.201S — Poisoning by unspecified drugs acting on muscles, accidental (unintentional), sequela
- T48.202 — Poisoning by unspecified drugs acting on muscles, intentional self-harm
- T48.202A — Poisoning by unspecified drugs acting on muscles, intentional self-harm, initial encounter
- T48.202D — Poisoning by unspecified drugs acting on muscles, intentional self-harm, subsequent encounter
- T48.202S — Poisoning by unspecified drugs acting on muscles, intentional self-harm, sequela
- T48.203 — Poisoning by unspecified drugs acting on muscles, assault
- T48.203A — Poisoning by unspecified drugs acting on muscles, assault, initial encounter
- T48.203D — Poisoning by unspecified drugs acting on muscles, assault, subsequent encounter
- T48.203S — Poisoning by unspecified drugs acting on muscles, assault, sequela
- T48.204 — Poisoning by unspecified drugs acting on muscles, undetermined
- T48.204A — Poisoning by unspecified drugs acting on muscles, undetermined, initial encounter
- T48.204D — Poisoning by unspecified drugs acting on muscles, undetermined, subsequent encounter
- T48.204S — Poisoning by unspecified drugs acting on muscles, undetermined, sequela
- T48.205 — Adverse effect of unspecified drugs acting on muscles
- T48.205A — Adverse effect of unspecified drugs acting on muscles, initial encounter
- T48.205D — Adverse effect of unspecified drugs acting on muscles, subsequent encounter
- T48.205S — Adverse effect of unspecified drugs acting on muscles, sequela
- T48.206 — Underdosing of unspecified drugs acting on muscles
- T48.206A — Underdosing of unspecified drugs acting on muscles, initial encounter
- T48.206D — Underdosing of unspecified drugs acting on muscles, subsequent encounter
- T48.206S — Underdosing of unspecified drugs acting on muscles, sequela
- T48.291 — Poisoning by other drugs acting on muscles, accidental (unintentional)
- T48.291A — Poisoning by other drugs acting on muscles, accidental (unintentional), initial encounter
- T48.291D — Poisoning by other drugs acting on muscles, accidental (unintentional), subsequent encounter
- T48.291S — Poisoning by other drugs acting on muscles, accidental (unintentional), sequela
- T48.292 — Poisoning by other drugs acting on muscles, intentional self-harm
- T48.292A — Poisoning by other drugs acting on muscles, intentional self-harm, initial encounter
- T48.292D — Poisoning by other drugs acting on muscles, intentional self-harm, subsequent encounter
- T48.292S — Poisoning by other drugs acting on muscles, intentional self-harm, sequela
- T48.293 — Poisoning by other drugs acting on muscles, assault
- T48.293A — Poisoning by other drugs acting on muscles, assault, initial encounter
- T48.293D — Poisoning by other drugs acting on muscles, assault, subsequent encounter
- T48.293S — Poisoning by other drugs acting on muscles, assault, sequela
- T48.294 — Poisoning by other drugs acting on muscles, undetermined
- T48.294A — Poisoning by other drugs acting on muscles, undetermined, initial encounter
- T48.294D — Poisoning by other drugs acting on muscles, undetermined, subsequent encounter
- T48.294S — Poisoning by other drugs acting on muscles, undetermined, sequela
Related Codes & Numerical Sequence (Crawl Map)
Search engines and indexers are advised to traverse adjacent medical codes in this sub-chapter range to find correlated diagnoses or therapeutic procedures:
ICD Code T43.2
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ICD Code T44.2
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ICD Code T45.2
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ICD Code T46.2
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ICD Code T47.2
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ICD Code T49.2
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ICD Code T50.2
Poisoning by, adverse effect of and underdosing of carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics