T88.1XXS ICD-10-CM Code: Other complications following immunization, not elsewhere classified, sequela
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- 7th character
- Required — see the character table on this page
- Tabular directives
- 2 inclusion terms · 1 Excludes1 · 36 Excludes2 · 3 use-additional codes
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.
- MS-DRG 922 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC (MDC 21)
- MS-DRG 923 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC (MDC 21)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for T88.1XXS in the official ICD-10-CM tabular list, quoted as published.
Notes without a marker are published on T88.1XXS itself; “inherited from” names the category or block whose note applies here.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Generalized vaccinia
- Rash following immunization
Source: inherited from T88.1
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- vaccinia not from vaccine (B08.011) Compare T88.1XXS vs B08.011 →
Source: inherited from T88.1
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- anaphylactic shock due to serum (T80.5-) inherited from T88.1Compare T88.1XXS vs T80.5 →
- other serum reactions (T80.6-) inherited from T88.1Compare T88.1XXS vs T80.6 →
- postimmunization arthropathy (M02.2) inherited from T88.1Compare T88.1XXS vs M02.2 →
- postimmunization encephalitis (G04.02) inherited from T88.1Compare T88.1XXS vs G04.02 →
- postimmunization fever (R50.83) inherited from T88.1Compare T88.1XXS vs R50.83 →
- complication following infusion, transfusion and therapeutic injection (T80.-) inherited from T88Compare T88.1XXS vs T80 →
- complication following procedure NEC (T81.-) inherited from T88Compare T88.1XXS vs T81 →
- complications of anesthesia in labor and delivery (O74.-) inherited from T88Compare T88.1XXS vs O74 →
- complications of anesthesia in pregnancy (O29.-) inherited from T88Compare T88.1XXS vs O29 →
- complications of anesthesia in puerperium (O89.-) inherited from T88Compare T88.1XXS vs O89 →
- complications of devices, implants and grafts (T82-T85) inherited from T88Compare T88.1XXS vs T82 →
- complications of obstetric surgery and procedure (O75.4) inherited from T88Compare T88.1XXS vs O75.4 →
- dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1) inherited from T88Compare T88.1XXS vs L23.3 →
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4) inherited from T88Compare T88.1XXS vs T36 →
- specified complications classified elsewhere inherited from T88
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-) inherited from T80-T88Compare T88.1XXS vs Z93 →
- closure of external stoma (Z43.-) inherited from T80-T88Compare T88.1XXS vs Z43 →
- fitting and adjustment of external prosthetic device (Z44.-) inherited from T80-T88Compare T88.1XXS vs Z44 →
- burns and corrosions from local applications and irradiation (T20-T32) inherited from T80-T88Compare T88.1XXS vs T20 →
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A) inherited from T80-T88Compare T88.1XXS vs O00 →
- mechanical complication of respirator ventilator
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6) inherited from T80-T88Compare T88.1XXS vs T36 →
- postprocedural fever (R50.82) inherited from T80-T88Compare T88.1XXS vs R50.82 →
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0) inherited from T80-T88Compare T88.1XXS vs G97.0 →
- colostomy malfunction (K94.0-) inherited from T80-T88Compare T88.1XXS vs K94.0 →
- disorders of fluid and electrolyte imbalance (E86-E87) inherited from T80-T88Compare T88.1XXS vs E86 →
- functional disturbances following cardiac surgery (I97.0-I97.1) inherited from T80-T88Compare T88.1XXS vs I97.0 →
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-) inherited from T80-T88Compare T88.1XXS vs D78 →
- ostomy complications (J95.0-, K94.-, N99.5-) inherited from T80-T88Compare T88.1XXS vs J95.0 →
- postgastric surgery syndromes (K91.1) inherited from T80-T88Compare T88.1XXS vs K91.1 →
- postlaminectomy syndrome NEC (M96.1) inherited from T80-T88Compare T88.1XXS vs M96.1 →
- postmastectomy lymphedema syndrome (I97.2) inherited from T80-T88Compare T88.1XXS vs I97.2 →
- postsurgical blind-loop syndrome (K91.2) inherited from T80-T88Compare T88.1XXS vs K91.2 →
- ventilator associated pneumonia (J95.851) inherited from T80-T88Compare T88.1XXS vs J95.851 →
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- Use additional code(s) to identify the specified condition resulting from the complication
- Use additional code to identify devices involved and details of circumstances (Y62-Y82)
Source: inherited from T80-T88
7th Character Guide
"The appropriate 7th character is to be added to each code from category T88"
- A — initial encounter
- D — subsequent encounter
- S — sequela (this page’s code)
How the encounter character is assigned. “Initial encounter” means the patient is receiving active treatment for the condition — it is not limited to the first visit, and a different or new provider giving active treatment still assigns it. “Subsequent encounter” covers care during the healing or recovery phase after active treatment. “Sequela” is for complications or conditions that arise as a direct result of the original condition.
ICD-10-CM Official Guidelines for Coding and Reporting, Section I.C.19.a (paraphrased by MedCoder).
Variant codes in this family
Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.
Coder workflow for T88.1XXS
MedCoder structured workflow — derived from this code’s own official record
Before you code T88.1XXS
- “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on T88.1XXS; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).
See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →
- A 7th character is required in this family. Confirm the documented encounter: initial (active treatment), subsequent (healing or recovery phase), or sequela. This page’s code carries “S”. “Initial” means active treatment, not the first visit (Guidelines I.C.19.a).
See the 7th Character Guide · Guide: 7th characters: initial, subsequent, sequela →
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with T88.1XXS. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support a condition named in T88.1XXS’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.ReviewB08.011
- Is the encounter phase documented — active treatment, healing or recovery, or a sequela?
Yes → Assign the matching 7th character; the variant codes are in the 7th Character Guide.
No → The code is invalid without its 7th character — query for the missing element.
Consider T88.1XXS. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- Encounter type
- Active treatment, healing or recovery phase, or sequela — the basis of the 7th character (Guidelines I.C.19.a).
- The conditions the Use Additional Code note names
- Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
- Any detail beyond this code’s title
- What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.
Official instructions as workflow
Excludes1 — check before selecting T88.1XXS(1 note)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with T88.1XXS: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareB08.011
See the official tabular notes · Guidelines I.A.12.a
Excludes2 — not part of T88.1XXS(36 notes)
Coding workflow: The conditions named in this note are not included in T88.1XXS. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
CompareT80.5, T80.6, M02.2, G04.02, R50.83, T80
See the official tabular notes · Guidelines I.A.12.b
Use Additional Code — after identifying T88.1XXS(3 notes)
Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with T88.1XXS when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.
See the official tabular notes · Guidelines I.A.13
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition T88.1XXS describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
ReviewB08.011
Documentation: The patient returns during the healing or recovery phase after active treatment of the same condition.
Coding question: Which 7th character applies?
Path: Review the official 7th-character definitions for this family in the 7th Character Guide.
Reason: “Initial encounter” means active treatment, not the first visit; care during recovery takes “subsequent encounter”, and a complication arising from the original condition takes “sequela” (Guidelines I.C.19.a).
Documentation: A condition the Use Additional Code note names is documented.
Coding question: Is a second code reported with T88.1XXS?
Path: Review the Use Additional Code note and the code it names.
Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Decision Points
The directives on this code's own record, as a pre-claim checklist.
- A 7th character applies in this family. Confirm the documented encounter matches the character assigned. See the official 7th-character definitions and this code’s variants
- 3 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
- 1 Excludes1 entry — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
- 36 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes
Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name T88.1XXS or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 3 Excludes2 notes: T78 — Adverse effects, not elsewhere classified (via T88.-), T79 — Certain early complications of trauma, not elsewhere classified (via T88.-), T81 — Complications of procedures, not elsewhere classified.
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
MS-DRG Grouper Relationships (FY2026)
Potential MS-DRG participation — not a DRG assignment.
Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.
Named in the grouper logic of 2 MS-DRGs: DRG 922 (MDC 21), DRG 923 (MDC 21).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):INJ076 — Complication, sequela (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same injury, other encounter phase
Same injury, coded at a different phase of treatment via the 7th character.
T88.1XXA — Other complications following immunization, not elsewhere classified, initial encounterCompare T88.1XXS vs T88.1XXA →, T88.1XXD — Other complications following immunization, not elsewhere classified, subsequent encounter
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Complication, sequela).
Contextual Map
Every relationship of T88.1XXS in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run T88.1XXS with these 3 related codes in Claim Check
Hierarchy
- S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T80-T88 — Complications of surgical and medical care, not elsewhere classified[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes2 notes
- T78 — Adverse effects, not elsewhere classified[Excludes2](via T88.-): “complications of surgical and medical care NEC (T80-T88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T79 — Certain early complications of trauma, not elsewhere classified[Excludes2](via T88.-): “complications occurring during or following medical procedures (T80-T88)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T81 — Complications of procedures, not elsewhere classified[Excludes2]: “complications following immunization (T88.0-T88.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Clinical classification (CCSR)
- INJ076 — Complication, sequela[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
MS-DRG Grouper
- DRG 922 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC[MS-DRG]: “OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC (MDC 21)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
- DRG 923 — OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC[MS-DRG]: “OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC (MDC 21)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
MDC crossing
- MDC 21 — Injuries, Poisonings and Toxic Effects of Drugs[MDC crossing]: “Injuries, Poisonings and Toxic Effects of Drugs — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 32,029 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026
Nearest codes (40)
- T88 — Other complications of surgical and medical care, not elsewhere classified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.0 — Infection following immunization[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.0XXA — Infection following immunization, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.0XXD — Infection following immunization, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.0XXS — Infection following immunization, sequela[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.1 — Other complications following immunization, not elsewhere classified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.1XXA — Other complications following immunization, not elsewhere classified, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- T88.1XXD — Other complications following immunization, not elsewhere classified, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 32 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Does T88.1XXS require a 7th character?
Yes. The appropriate 7th character is to be added to each code from category T88.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionOther complications following immunization, not elsewhere classified, sequela
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to T88.1XXS in its code family, with their registry titles.
- T88.0XXD — Infection following immunization, subsequent encounter
- T88.0XXS — Infection following immunization, sequela
- T88.1 — Other complications following immunization, not elsewhere classified
- T88.1XXA — Other complications following immunization, not elsewhere classified, initial encounter
- T88.1XXD — Other complications following immunization, not elsewhere classified, subsequent encounter
- T88.2 — Shock due to anesthesia
- T88.2XXA — Shock due to anesthesia, initial encounter
- T88.2XXD — Shock due to anesthesia, subsequent encounter
- T88.2XXS — Shock due to anesthesia, sequela
- T88.3 — Malignant hyperthermia due to anesthesia