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Inpatient Procedure Code

3E0L4GC ICD-10-PCS Code: Introduction of Other Therapeutic Substance into Pleural Cavity, Percutaneous Endoscopic Approach

Introduce Oth Therap Subst in Pleural Cav, Perc Endo

Axis Breakdown

Every ICD-10-PCS code is exactly seven characters, one per axis. Each character's meaning is defined by its position in the code.

PositionValueMeaning
1
Section3

Administration

2
Body SystemE

Physiological Systems and Anatomical Regions

3
Root Operation0

Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4
Body System / RegionL

Pleural Cavity

5
Approach4

Percutaneous Endoscopic

6
SubstanceG

Other Therapeutic Substance

7
QualifierC

Other Substance

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

The MS-DRG grouper treats this as an operating room procedure. It appears in the surgical logic of 4 MS-DRGs:

From the CMS MS-DRG Definitions Manual, Appendix E. Actual DRG assignment depends on the complete claim.

Related Codes

Same operation — other Body System / Region

Same table and root operation, differing only in the body system / region character.

3E0G4GC — Introduction of Other Therapeutic Substance into Upper GI, Percutaneous Endoscopic Approach, 3E0H4GC — Introduction of Other Therapeutic Substance into Lower GI, Percutaneous Endoscopic Approach, 3E0J4GC — Introduction of Other Therapeutic Substance into Biliary and Pancreatic Tract, Percutaneous Endoscopic Approach, 3E0K4GC — Introduction of Other Therapeutic Substance into Genitourinary Tract, Percutaneous Endoscopic Approach, 3E0M4GC — Introduction of Other Therapeutic Substance into Peritoneal Cavity, Percutaneous Endoscopic Approach, 3E0N4GC — Introduction of Other Therapeutic Substance into Male Reproductive, Percutaneous Endoscopic Approach, 3E0P4GC — Introduction of Other Therapeutic Substance into Female Reproductive, Percutaneous Endoscopic Approach, 3E0U4GC — Introduction of Other Therapeutic Substance into Joints, Percutaneous Endoscopic Approach, +6 more

Same operation — other Approach

Same table and root operation, differing only in the approach character.

3E0L3GC — Introduction of Other Therapeutic Substance into Pleural Cavity, Percutaneous Approach

Same procedure category (CCSR), other tables

AHRQ's Clinical Classifications Software Refined groups these ICD-10-PCS procedures with this one under Administration of therapeutic substances, NEC (Administration of Therapeutic Substances); listed here are the members in other PCS tables. Source: Clinical Classifications Software Refined (CCSR), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, November 2025.

XW00X27 — Introduction of Anacaulase-bcdb into Skin, External Approach, New Technology Group 7, XW0136A — Introduction of Dasiglucagon into Subcutaneous Tissue, Percutaneous Approach, New Technology Group 10, XW01397 — Introduction of Satralizumab-mwge into Subcutaneous Tissue, Percutaneous Approach, New Technology Group 7, XW013TB — Introduction of Rozanolixizumab-noli Monoclonal Antibody into Subcutaneous Tissue, Percutaneous Approach, New Technology Group 11, XW013W5 — Introduction of Caplacizumab into Subcutaneous Tissue, Percutaneous Approach, New Technology Group 5, XW01X27 — Introduction of Anacaulase-bcdb into Subcutaneous Tissue, External Approach, New Technology Group 7, XW0333A — Introduction of Bentracimab, Ticagrelor Reversal Agent into Peripheral Vein, Percutaneous Approach, New Technology Group 10, XW03372 — Introduction of Inactivated Coagulation Factor Xa into Peripheral Vein, Percutaneous Approach, New Technology Group 2, XW03377 — Introduction of Trilaciclib into Peripheral Vein, Percutaneous Approach, New Technology Group 7, XW033F3 — Introduction of Other New Technology Therapeutic Substance into Peripheral Vein, Percutaneous Approach, New Technology Group 3, XW033FA — Introduction of Non-Chimeric Antigen Receptor T-cell Immune Effector Cell Therapy into Peripheral Vein, Percutaneous Approach, New Technology Group 10, XW033FB — Introduction of Valoctocogene Roxaparvovec-rvox into Peripheral Vein, Percutaneous Approach, New Technology Group 11, XW033MA — Introduction of Emapalumab-lzsg Anti-IFNy Monoclonal Antibody into Peripheral Vein, Percutaneous Approach, New Technology Group 10, XW033Q9 — Introduction of Posoleucel into Peripheral Vein, Percutaneous Approach, New Technology Group 9, XW033QB — Introduction of Iloprost into Peripheral Vein, Percutaneous Approach, New Technology Group 11, XW033R9 — Introduction of Rezafungin into Peripheral Vein, Percutaneous Approach, New Technology Group 9, XW033W5 — Introduction of Caplacizumab into Peripheral Vein, Percutaneous Approach, New Technology Group 5, XW0433A — Introduction of Bentracimab, Ticagrelor Reversal Agent into Central Vein, Percutaneous Approach, New Technology Group 10, XW04372 — Introduction of Inactivated Coagulation Factor Xa into Central Vein, Percutaneous Approach, New Technology Group 2, XW04377 — Introduction of Trilaciclib into Central Vein, Percutaneous Approach, New Technology Group 7, +38 more

Contextual Map

Every relationship of 3E0L4GC in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run 3E0L4GC with these 5 related codes in Claim Check

PCS table

MS-DRG participation

Clinical classification (CCSR)

MDC crossing · diagnoses (2525)

  • MDC 04 — Diseases and Disorders of the Respiratory System[MDC crossing]: “Diseases and Disorders of the Respiratory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
  • MDC 05 — Diseases and Disorders of the Circulatory System[MDC crossing]: “Diseases and Disorders of the Circulatory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
  • A02.22 — Salmonella pneumonia[Same-MDC diagnosis]: “Salmonella pneumonia — grouped in MDC 04, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A06.5 — Amebic lung abscess[Same-MDC diagnosis]: “Amebic lung abscess — grouped in MDC 04, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A15.0 — Tuberculosis of lung[Same-MDC diagnosis]: “Tuberculosis of lung — grouped in MDC 04, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A15.4 — Tuberculosis of intrathoracic lymph nodes[Same-MDC diagnosis]: “Tuberculosis of intrathoracic lymph nodes — grouped in MDC 04, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • A15.5 — Tuberculosis of larynx, trachea and bronchus[Same-MDC diagnosis]: “Tuberculosis of larynx, trachea and bronchus — grouped in MDC 04, the diagnosis side of this code's crossing.”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
  • and 2520 more

Nearest codes

Change history

No changes recorded for this code. This ledger tracks additions, deletions and description changes from FY2026 (April) onward. Note changes are not tracked.

Read from: CMS ICD-10-PCS code tables, index and definitions — FY2026 (April); CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43; AHRQ HCUP Clinical Classifications Software Refined for ICD-10-PCS Procedures (hcup-us.ahrq.gov/toolssoftware/ccsr/PRCCSR_v2026-1.zip) — v2026.1. All data sources · How to read the labels