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Compare/A40 vs A41.81

A40 vs A41.81

A40 (Streptococcal sepsis) compared with A41.81 (Sepsis due to Enterococcus), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. A40 carries an Excludes1 note covering A41.81: “sepsis due to Streptococcus, group D (A41.81)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

No — do not report together. A41.81 carries an Excludes1 note covering A40: “streptococcal sepsis (A40.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

A40Streptococcal sepsisA41.81Sepsis due to Enterococcus
Billing statusNon-billable header

Report instead: A40.0, A40.1, A40.3, A40.8, A40.9

Billable
ClassificationA00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)A00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)
DefinitionStreptococcal sepsis is a non-billable ICD-10-CM category code (A40).Sepsis due to Enterococcus is a billable ICD-10-CM diagnosis code (A41.81).
Code first
, if applicable, postprocedural sepsis (T81.44-)
sepsis due to central venous catheter (T80.211-)
, if applicable, postprocedural sepsis (T81.44-)
sepsis due to central venous catheter (T80.211-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources