A52.75 vs N16
A52.75 (Syphilis of kidney and ureter) compared with N16 (Renal tubulo-interstitial disorders in diseases classified elsewhere), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. N16 carries an Excludes1 note covering A52.75: “syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| A52.75Syphilis of kidney and ureter | N16Renal tubulo-interstitial disorders in diseases classified elsewhere | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | A00-B99 — Certain Infectious and Parasitic Diseases (A00-B99) | N00-N99 — Diseases of the Genitourinary System (N00-N99) |
| Definition | Syphilis of kidney and ureter is a billable ICD-10-CM diagnosis code (A52.75). | Renal tubulo-interstitial disorders in diseases classified elsewhere is a billable ICD-10-CM diagnosis code (N16). |
| Includes | Syphilitic glomerular disease | pyelonephritis Pyelonephritis Tubulo-interstitial nephritis |
| Code first | — | underlying disease, such as: brucellosis (A23.0-A23.9) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources