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Compare/A52.78 vs M63

A52.78 vs M63

A52.78 (Syphilis of other musculoskeletal tissue) compared with M63 (Disorders of muscle in diseases classified elsewhere), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. M63 carries an Excludes1 note covering A52.78: “myopathy in syphilis (late) (A52.78)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

A52.78Syphilis of other musculoskeletal tissueM63Disorders of muscle in diseases classified elsewhere
Billing statusBillableNon-billable header

Report instead: M63.80, M63.811, M63.812, M63.819, M63.821

ClassificationA00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)M00-M99 — Diseases of the Musculoskeletal System and Connective Tissue (M00-M99)
DefinitionSyphilis of other musculoskeletal tissue is a billable ICD-10-CM diagnosis code (A52.78).Disorders of muscle in diseases classified elsewhere is a non-billable ICD-10-CM category code (M63).
Includes
Late syphilitic bursitis
Syphilis [stage unspecified] of bursa
Syphilis [stage unspecified] of muscle
Syphilis [stage unspecified] of synovium
Code first
underlying disease, such as:
leprosy (A30.-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources