B00 vs B27.0

B00 (Herpesviral [herpes simplex] infections) compared with B27.0 (Gammaherpesviral mononucleosis), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. B00 carries an Excludes2 note covering B27.0: “gammaherpesviral mononucleosis (B27.0-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

	B00Herpesviral [herpes simplex] infections	B27.0Gammaherpesviral mononucleosis
Billing status	Non-billable header Report instead: B00.0, B00.1, B00.2, B00.3, B00.4	Non-billable header Report instead: B27.00, B27.01, B27.02, B27.09
Classification	A00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)	A00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)
Definition	Herpesviral [herpes simplex] infections is a non-billable ICD-10-CM category code (B00).	Gammaherpesviral mononucleosis is a non-billable ICD-10-CM category code (B27.0).
Includes	—	glandular fever monocytic angina Pfeiffer's disease Mononucleosis due to Epstein-Barr virus

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources