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Compare/B00.4 vs B10.0

B00.4 vs B10.0

B00.4 (Herpesviral encephalitis) compared with B10.0 (Other human herpesvirus encephalitis), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. B00.4 carries an Excludes1 note covering B10.0: “non-simplex herpesviral encephalitis (B10.0-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “herpes encephalitis NOS (B00.4)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “herpes simplex encephalitis (B00.4)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “human herpesvirus encephalitis (B00.4)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “simian B herpes virus encephalitis (B00.4)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “herpes simplex (B00.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “human herpesvirus NOS (B00.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Yes, when both are documented. B10.0 carries an Excludes2 note covering B00.4: “human herpesvirus 1 and 2 (B00.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

B00.4Herpesviral encephalitisB10.0Other human herpesvirus encephalitis
Billing statusBillableNon-billable header

Report instead: B10.01, B10.09

ClassificationA00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)A00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)
DefinitionHerpesviral encephalitis is a billable ICD-10-CM diagnosis code (B00.4).Other human herpesvirus encephalitis is a non-billable ICD-10-CM category code (B10.0).
Includes
Herpesviral meningoencephalitis
Simian B disease

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources