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B20 vs D89.40

B20 (Human immunodeficiency virus [HIV] disease) compared with D89.40 (Mast cell activation, unspecified), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. D89.40 carries an Excludes2 note covering B20: “human immunodeficiency virus [HIV] disease (B20)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

B20Human immunodeficiency virus [HIV] diseaseD89.40Mast cell activation, unspecified
Billing statusBillableBillable
ClassificationA00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionHuman immunodeficiency virus [HIV] disease is a billable ICD-10-CM diagnosis code (B20).Mast cell activation, unspecified is a billable ICD-10-CM diagnosis code (D89.40).
Includes
acquired immune deficiency syndrome [AIDS]
AIDS-related complex [ARC]
HIV infection, symptomatic
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis
Mast cell activation disorder, unspecified
Use additional code
code(s) to identify all manifestations of HIV infection
Code first
Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources