Skip to main content

B20 vs D89.831

B20 (Human immunodeficiency virus [HIV] disease) compared with D89.831 (Cytokine release syndrome, grade 1), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. D89.831 carries an Excludes2 note covering B20: “human immunodeficiency virus [HIV] disease (B20)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

B20Human immunodeficiency virus [HIV] diseaseD89.831Cytokine release syndrome, grade 1
Billing statusBillableBillable
ClassificationA00-B99 — Certain Infectious and Parasitic Diseases (A00-B99)D50-D89 — Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)
DefinitionHuman immunodeficiency virus [HIV] disease is a billable ICD-10-CM diagnosis code (B20).Cytokine release syndrome, grade 1 is a billable ICD-10-CM diagnosis code (D89.831).
Includes
acquired immune deficiency syndrome [AIDS]
AIDS-related complex [ARC]
HIV infection, symptomatic
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis
Use additional code
code(s) to identify all manifestations of HIV infection
code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
code to identify associated manifestations
Code first
Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
underlying cause, such as:
complications following infusion, transfusion and therapeutic injection (T80.89-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources