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C00.5 vs D00.01

C00.5 (Malignant neoplasm of lip, unspecified, inner aspect) compared with D00.01 (Carcinoma in situ of labial mucosa and vermilion border), from the official CMS tabular data. C00.5 and D00.01 name the same anatomical site (lip) with a different neoplasm behavior. MedCoder-derived

Relationship

Informational

Neoplasm table relationship

C00.5
Malignant neoplasm of lip, unspecified, inner aspect
D00.01
Carcinoma in situ of labial mucosa and vermilion border

Same anatomical site, different neoplasm behavior.

Same site — carcinoma in situ (lip)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C00.5 and D00.01 name the same anatomical site (lip) with a different neoplasm behavior.

From the CMS/CDC Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C00.5Malignant neoplasm of lip, unspecified, inner aspectD00.01Carcinoma in situ of labial mucosa and vermilion border
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of lip, unspecified, inner aspect is a billable ICD-10-CM diagnosis code (C00.5).Carcinoma in situ of labial mucosa and vermilion border is a billable ICD-10-CM diagnosis code (D00.01).
Includes
Malignant neoplasm of buccal aspect of lip, unspecified
Malignant neoplasm of frenulum of lip, unspecified
Malignant neoplasm of mucosa of lip, unspecified
Malignant neoplasm of oral aspect of lip, unspecified
Bowen's disease
erythroplasia
grade III intraepithelial neoplasia
Queyrat's erythroplasia
Use additional code
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco dependence (Z87.891)
code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources