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C25.7 vs C78.89

C25.7 (Malignant neoplasm of other parts of pancreas) compared with C78.89 (Secondary malignant neoplasm of other digestive organs), from the official CMS tabular data. C25.7 and C78.89 name the same anatomical site (pancreas) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C78.89
Secondary malignant neoplasm of other digestive organs
C25.7
Malignant neoplasm of other parts of pancreas

Same anatomical site, different neoplasm behavior.

Same site — primary malignancy (pancreas)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C78.89 and C25.7 name the same anatomical site (pancreas) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C25.7Malignant neoplasm of other parts of pancreasC78.89Secondary malignant neoplasm of other digestive organs
Billing statusBillableBillable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of other parts of pancreas is a billable ICD-10-CM diagnosis code (C25.7).Secondary malignant neoplasm of other digestive organs is a billable ICD-10-CM diagnosis code (C78.89).
Includes
Malignant neoplasm of neck of pancreas
Use additional code
code to identify:
alcohol abuse and dependence (F10.-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources