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C38.0 vs C49.A1

C38.0 (Malignant neoplasm of heart) compared with C49.A1 (Gastrointestinal stromal tumor of esophagus), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C49.A1 carries an Excludes2 note covering C38.0: “malignant neoplasm of heart (C38.0)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C38.0Malignant neoplasm of heartC49.A1Gastrointestinal stromal tumor of esophagus
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of heart is a billable ICD-10-CM diagnosis code (C38.0).Gastrointestinal stromal tumor of esophagus is a billable ICD-10-CM diagnosis code (C49.A1).
Includes
malignant neoplasm of middle ear
Malignant neoplasm of pericardium
malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources