Skip to main content

C38.2 vs D49.89

C38.2 (Malignant neoplasm of posterior mediastinum) compared with D49.89 (Neoplasm of unspecified behavior of other specified sites), from the official CMS tabular data. C38.2 and D49.89 name the same anatomical site (mediastinum) with a different neoplasm behavior. MedCoder-derived

Relationship

Informational

Neoplasm table relationship

D49.89
Neoplasm of unspecified behavior of other specified sites
C38.2
Malignant neoplasm of posterior mediastinum

Same anatomical site, different neoplasm behavior.

Same site — primary malignancy (mediastinum)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. D49.89 and C38.2 name the same anatomical site (mediastinum) with a different neoplasm behavior.

From the CMS/CDC Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C38.2Malignant neoplasm of posterior mediastinumD49.89Neoplasm of unspecified behavior of other specified sites
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of posterior mediastinum is a billable ICD-10-CM diagnosis code (C38.2).Neoplasm of unspecified behavior of other specified sites is a billable ICD-10-CM diagnosis code (D49.89).
Includes
malignant neoplasm of middle ear
'growth' NOS
neoplasm NOS
new growth NOS
tumor NOS

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources