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C40.2 vs C79.51

C40.2 (Malignant neoplasm of long bones of lower limb) compared with C79.51 (Secondary malignant neoplasm of bone), from the official CMS tabular data. C40.2 and C79.51 name the same anatomical site (bone) with a different neoplasm behavior. MedCoder-derived

Relationship

Informational

Neoplasm table relationship

C40.2
Malignant neoplasm of long bones of lower limb
C79.51
Secondary malignant neoplasm of bone

Same anatomical site, different neoplasm behavior.

Same site — secondary malignancy (bone)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C40.2 and C79.51 name the same anatomical site (bone) with a different neoplasm behavior.

From the CMS/CDC Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C40.2Malignant neoplasm of long bones of lower limbC79.51Secondary malignant neoplasm of bone
Billing statusNon-billable header

Report instead: C40.20, C40.21, C40.22

Billable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of long bones of lower limb is a non-billable ICD-10-CM category code (C40.2).Secondary malignant neoplasm of bone is a billable ICD-10-CM diagnosis code (C79.51).
Includes
malignant neoplasm of cartilage (articular) (joint)
malignant neoplasm of periosteum
Use additional code
code to identify major osseous defect, if applicable (M89.7-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources