C41.9 vs D48.0

C41.9 (Malignant neoplasm of bone and articular cartilage, unspecified) compared with D48.0 (Neoplasm of uncertain behavior of bone and articular cartilage), from the official CMS tabular data. C41.9 and D48.0 name the same anatomical site (bone) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C41.9

Malignant neoplasm of bone and articular cartilage, unspecified

↔

D48.0

Neoplasm of uncertain behavior of bone and articular cartilage

Same anatomical site, different neoplasm behavior.

Same site — uncertain behavior (bone)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C41.9 and D48.0 name the same anatomical site (bone) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

	C41.9Malignant neoplasm of bone and articular cartilage, unspecified	D48.0Neoplasm of uncertain behavior of bone and articular cartilage
Billing status	Billable	Billable
Classification	C00-D49 — Neoplasms	C00-D49 — Neoplasms
Definition	Malignant neoplasm of bone and articular cartilage, unspecified is a billable ICD-10-CM diagnosis code (C41.9).	Neoplasm of uncertain behavior of bone and articular cartilage is a billable ICD-10-CM diagnosis code (D48.0).
Includes	malignant neoplasm of cartilage (articular) (joint) malignant neoplasm of periosteum	—

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources