C43 vs C51

C43 (Malignant melanoma of skin) compared with C51 (Malignant neoplasm of vulva), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C43 carries an Excludes2 note covering C51: “malignant melanoma of skin of genital organs (C51-C52, C60.-, C63.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

	C43Malignant melanoma of skin	C51Malignant neoplasm of vulva
Billing status	Non-billable header Report instead: C43.0, C43.10, C43.111, C43.112, C43.121	Non-billable header Report instead: C51.0, C51.1, C51.2, C51.8, C51.9
Classification	C00-D49 — Neoplasms (C00-D49)	C00-D49 — Neoplasms (C00-D49)
Definition	Malignant melanoma of skin is a non-billable ICD-10-CM category code (C43).	Malignant neoplasm of vulva is a non-billable ICD-10-CM category code (C51).
Includes	—	malignant neoplasm of skin of female genital organs

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Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources