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Compare/C47 vs C49

C47 vs C49

C47 (Malignant neoplasm of peripheral nerves and autonomic nervous system) compared with C49 (Malignant neoplasm of other connective and soft tissue), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C49 carries an Excludes2 note covering C47: “malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C47Malignant neoplasm of peripheral nerves and autonomic nervous systemC49Malignant neoplasm of other connective and soft tissue
Billing statusNon-billable header

Report instead: C47.0, C47.10, C47.11, C47.12, C47.20

Non-billable header

Report instead: C49.0, C49.10, C49.11, C49.12, C49.20

ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of peripheral nerves and autonomic nervous system is a non-billable ICD-10-CM category code (C47).Malignant neoplasm of other connective and soft tissue is a non-billable ICD-10-CM category code (C49).
Includes
malignant neoplasm of sympathetic and parasympathetic nerves and ganglia
malignant neoplasm of blood vessel
malignant neoplasm of bursa
malignant neoplasm of cartilage
malignant neoplasm of fascia

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources