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C48.1 vs D49.0

C48.1 (Malignant neoplasm of specified parts of peritoneum) compared with D49.0 (Neoplasm of unspecified behavior of digestive system), from the official CMS tabular data. C48.1 and D49.0 name the same anatomical site (cul-de-sac) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C48.1
Malignant neoplasm of specified parts of peritoneum
D49.0
Neoplasm of unspecified behavior of digestive system

Same anatomical site, different neoplasm behavior.

Same site — unspecified behavior (cul-de-sac)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C48.1 and D49.0 name the same anatomical site (cul-de-sac) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C48.1Malignant neoplasm of specified parts of peritoneumD49.0Neoplasm of unspecified behavior of digestive system
Billing statusBillableBillable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of specified parts of peritoneum is a billable ICD-10-CM diagnosis code (C48.1).Neoplasm of unspecified behavior of digestive system is a billable ICD-10-CM diagnosis code (D49.0).
Includes
Malignant neoplasm of cul-de-sac
Malignant neoplasm of mesentery
Malignant neoplasm of mesocolon
Malignant neoplasm of omentum
'growth' NOS
neoplasm NOS
new growth NOS
tumor NOS

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources