C49.A1 vs C50
C49.A1 (Gastrointestinal stromal tumor of esophagus) compared with C50 (Malignant neoplasm of breast), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.
Can these codes be reported together?
No — do not report together. C49.A1 carries an Excludes1 note covering C50: “malignant neoplasm of connective tissue of breast (C50.-)”
Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
Side by side
| C49.A1Gastrointestinal stromal tumor of esophagus | C50Malignant neoplasm of breast | |
|---|---|---|
| Billing status | Billable | Non-billable header |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Gastrointestinal stromal tumor of esophagus is a billable ICD-10-CM diagnosis code (C49.A1). | Malignant neoplasm of breast is a non-billable ICD-10-CM category code (C50). |
| Includes | malignant neoplasm of blood vessel malignant neoplasm of bursa malignant neoplasm of cartilage malignant neoplasm of fascia | connective tissue of breast Paget's disease of breast Paget's disease of nipple |
| Use additional code | — | code to identify estrogen, and other hormones and factors receptor status (Z17.-) |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources