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C50.4 vs D05

C50.4 (Malignant neoplasm of upper-outer quadrant of breast) compared with D05 (Carcinoma in situ of breast), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1. MedCoder-derived

Relationship

Conflict

Excludes1 conflict

D05
Carcinoma in situ of breast
C50.4
Malignant neoplasm of upper-outer quadrant of breast

Not coded here — these two are mutually exclusive.

“Paget's disease of breast or nipple (C50.-)”

An Excludes1 note means the two conditions cannot occur together, so the pair should not be reported for the same encounter. The sole exception is when the conditions are documented as unrelated to each other.

Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a

Can these codes be reported together?

No — do not report together. D05 carries an Excludes1 note covering C50.4: “Paget's disease of breast or nipple (C50.-)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

C50.4Malignant neoplasm of upper-outer quadrant of breastD05Carcinoma in situ of breast
Billing statusNon-billable header

Report instead: C50.411, C50.412, C50.419, C50.421, C50.422

Non-billable header

Report instead: D05.00, D05.01, D05.02, D05.10, D05.11

ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of upper-outer quadrant of breast is a non-billable ICD-10-CM category code (C50.4).Carcinoma in situ of breast is a non-billable ICD-10-CM category code (D05).
Includes
connective tissue of breast
Paget's disease of breast
Paget's disease of nipple
Bowen's disease
erythroplasia
grade III intraepithelial neoplasia
Queyrat's erythroplasia
Use additional code
code to identify estrogen, and other hormones and factors receptor status (Z17.-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources