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C53.1 vs Z12.4

C53.1 (Malignant neoplasm of exocervix) compared with Z12.4 (Encounter for screening for malignant neoplasm of cervix), from the official CMS tabular data. Z12.4 is the personal-history/screening code for the active disease C53.1 names.

Relationship

Review

Condition lifecycle relationship

Z12.4
Encounter for screening for malignant neoplasm of cervix
C53.1
Malignant neoplasm of exocervix

Personal-history or screening code versus the active disease.

Active disease for this site (cervix)

A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code for the same site.

Source: CMS Table of Neoplasms (site match derived from the code title)

Can these codes be reported together?

History or screening versus active disease. Z12.4 is the personal-history or screening code for the active disease C53.1 names.

Site match derived from the code’s own title against the CMS Table of Neoplasms. A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code.

Side by side

C53.1Malignant neoplasm of exocervixZ12.4Encounter for screening for malignant neoplasm of cervix
Billing statusBillableBillable
ClassificationC00-D49 — NeoplasmsZ00-Z99 — Factors influencing health status and contact with health services
DefinitionMalignant neoplasm of exocervix is a billable ICD-10-CM diagnosis code (C53.1).Encounter for screening for malignant neoplasm of cervix is a billable ICD-10-CM diagnosis code (Z12.4).
Includes
malignant neoplasm of skin of female genital organs
Encounter for screening pap smear for malignant neoplasm of cervix
Use additional code
code to identify any family history of malignant neoplasm (Z80.-)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources