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C64 vs Z80.51

C64 (Malignant neoplasm of kidney, except renal pelvis) compared with Z80.51 (Family history of malignant neoplasm of kidney), from the official CMS tabular data. Z80.51 is the personal-history/screening code for the active disease C64 names. MedCoder-derived

Relationship

Review

Condition lifecycle relationship

Z80.51
Family history of malignant neoplasm of kidney
C64
Malignant neoplasm of kidney, except renal pelvis

Personal-history or screening code versus the active disease.

Active disease for this site (kidney)

A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code for the same site.

Source: CMS Table of Neoplasms (site match derived from the code title)

Can these codes be reported together?

History or screening versus active disease. Z80.51 is the personal-history or screening code for the active disease C64 names.

Site match derived from the code’s own title against the CMS/CDC Table of Neoplasms. A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code.

Side by side

C64Malignant neoplasm of kidney, except renal pelvisZ80.51Family history of malignant neoplasm of kidney
Billing statusNon-billable header

Report instead: C64.1, C64.2, C64.9

Billable
ClassificationC00-D49 — Neoplasms (C00-D49)Z00-Z99 — Factors Influencing Health Status and Contact with Health Services (Z00-Z99)
DefinitionMalignant neoplasm of kidney, except renal pelvis is a non-billable ICD-10-CM category code (C64).Family history of malignant neoplasm of kidney is a billable ICD-10-CM diagnosis code (Z80.51).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources