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C65 vs D41.1

C65 (Malignant neoplasm of renal pelvis) compared with D41.1 (Neoplasm of uncertain behavior of renal pelvis), from the official CMS tabular data. C65 and D41.1 name the same anatomical site (calyx) with a different neoplasm behavior. MedCoder-derived

Relationship

Informational

Neoplasm table relationship

C65
Malignant neoplasm of renal pelvis
D41.1
Neoplasm of uncertain behavior of renal pelvis

Same anatomical site, different neoplasm behavior.

Same site — uncertain behavior (calyx)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C65 and D41.1 name the same anatomical site (calyx) with a different neoplasm behavior.

From the CMS/CDC Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C65Malignant neoplasm of renal pelvisD41.1Neoplasm of uncertain behavior of renal pelvis
Billing statusNon-billable header

Report instead: C65.1, C65.2, C65.9

Non-billable header

Report instead: D41.10, D41.11, D41.12

ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of renal pelvis is a non-billable ICD-10-CM category code (C65).Neoplasm of uncertain behavior of renal pelvis is a non-billable ICD-10-CM category code (D41.1).
Includes
malignant neoplasm of pelviureteric junction
malignant neoplasm of renal calyces

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources