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C65 vs Z80.51

C65 (Malignant neoplasm of renal pelvis) compared with Z80.51 (Family history of malignant neoplasm of kidney), from the official CMS tabular data. Z80.51 is the personal-history/screening code for the active disease C65 names. MedCoder-derived

Relationship

Review

Condition lifecycle relationship

Z80.51
Family history of malignant neoplasm of kidney
C65
Malignant neoplasm of renal pelvis

Personal-history or screening code versus the active disease.

Active disease for this site (kidney)

A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code for the same site.

Source: CMS Table of Neoplasms (site match derived from the code title)

Can these codes be reported together?

History or screening versus active disease. Z80.51 is the personal-history or screening code for the active disease C65 names.

Site match derived from the code’s own title against the CMS/CDC Table of Neoplasms. A personal-history code describes a condition that no longer exists and is no longer being treated, so it is not interchangeable with the active-disease code.

Side by side

C65Malignant neoplasm of renal pelvisZ80.51Family history of malignant neoplasm of kidney
Billing statusNon-billable header

Report instead: C65.1, C65.2, C65.9

Billable
ClassificationC00-D49 — NeoplasmsZ00-Z99 — Factors influencing health status and contact with health services
DefinitionMalignant neoplasm of renal pelvis is a non-billable ICD-10-CM category code (C65).Family history of malignant neoplasm of kidney is a billable ICD-10-CM diagnosis code (Z80.51).
Includes
malignant neoplasm of pelviureteric junction
malignant neoplasm of renal calyces

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources