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C72.2 vs D43.3

C72.2 (Malignant neoplasm of olfactory nerve) compared with D43.3 (Neoplasm of uncertain behavior of cranial nerves), from the official CMS tabular data. C72.2 and D43.3 name the same anatomical site (olfactory nerve or bulb) with a different neoplasm behavior. MedCoder-derived

Relationship

Informational

Neoplasm table relationship

C72.2
Malignant neoplasm of olfactory nerve
D43.3
Neoplasm of uncertain behavior of cranial nerves

Same anatomical site, different neoplasm behavior.

Same site — uncertain behavior (olfactory nerve or bulb)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C72.2 and D43.3 name the same anatomical site (olfactory nerve or bulb) with a different neoplasm behavior.

From the CMS/CDC Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C72.2Malignant neoplasm of olfactory nerveD43.3Neoplasm of uncertain behavior of cranial nerves
Billing statusNon-billable header

Report instead: C72.20, C72.21, C72.22

Billable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of olfactory nerve is a non-billable ICD-10-CM category code (C72.2).Neoplasm of uncertain behavior of cranial nerves is a billable ICD-10-CM diagnosis code (D43.3).
Includes
Malignant neoplasm of olfactory bulb

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources