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C72.59 vs D43.3

C72.59 (Malignant neoplasm of other cranial nerves) compared with D43.3 (Neoplasm of uncertain behavior of cranial nerves), from the official CMS tabular data. C72.59 and D43.3 name the same anatomical site (cranial) with a different neoplasm behavior.

Relationship

Informational

Neoplasm table relationship

C72.59
Malignant neoplasm of other cranial nerves
D43.3
Neoplasm of uncertain behavior of cranial nerves

Same anatomical site, different neoplasm behavior.

Same site — uncertain behavior (cranial)

The behavior documented for the site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column of the neoplasm table, and therefore which code, applies.

Source: CMS Table of Neoplasms

Can these codes be reported together?

Same site, different neoplasm behavior. C72.59 and D43.3 name the same anatomical site (cranial) with a different neoplasm behavior.

From the CMS Table of Neoplasms: the behavior documented for that site — malignant primary, secondary, carcinoma in situ, benign, uncertain or unspecified — decides which column, and therefore which code, applies.

Side by side

C72.59Malignant neoplasm of other cranial nervesD43.3Neoplasm of uncertain behavior of cranial nerves
Billing statusBillableBillable
ClassificationC00-D49 — NeoplasmsC00-D49 — Neoplasms
DefinitionMalignant neoplasm of other cranial nerves is a billable ICD-10-CM diagnosis code (C72.59).Neoplasm of uncertain behavior of cranial nerves is a billable ICD-10-CM diagnosis code (D43.3).

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources