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Compare/C76 vs C80.1

C76 vs C80.1

C76 (Malignant neoplasm of other and ill-defined sites) compared with C80.1 (Malignant (primary) neoplasm, unspecified), from the official CMS tabular data. Do not report these codes together: the official tabular list marks them Excludes1.

Can these codes be reported together?

No — do not report together. C76 carries an Excludes1 note covering C80.1: “malignant neoplasm of unspecified site NOS (C80.1)”

Sole exception: when the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Side by side

C76Malignant neoplasm of other and ill-defined sitesC80.1Malignant (primary) neoplasm, unspecified
Billing statusNon-billable header

Report instead: C76.0, C76.1, C76.2, C76.3, C76.40

Billable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionMalignant neoplasm of other and ill-defined sites is a non-billable ICD-10-CM category code (C76).Malignant (primary) neoplasm, unspecified is a billable ICD-10-CM diagnosis code (C80.1).
Includes
Cancer NOS
Cancer unspecified site (primary)
Carcinoma unspecified site (primary)
Malignancy unspecified site (primary)

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources