C78.89 vs C81.38
C78.89 (Secondary malignant neoplasm of other digestive organs) compared with C81.38 (Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).
Can these codes be reported together?
Yes, when both are documented. C81.38 carries an Excludes2 note covering C78.89: “secondary neoplasm of spleen (C78.89)”
Excludes2 marks distinct conditions — both may be reported when both are documented.
Side by side
| C78.89Secondary malignant neoplasm of other digestive organs | C81.38Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites | |
|---|---|---|
| Billing status | Billable | Billable |
| Classification | C00-D49 — Neoplasms (C00-D49) | C00-D49 — Neoplasms (C00-D49) |
| Definition | Secondary malignant neoplasm of other digestive organs is a billable ICD-10-CM diagnosis code (C78.89). | Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites is a billable ICD-10-CM diagnosis code (C81.38). |
Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources