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Compare/C78.89 vs C88.00

C78.89 vs C88.00

C78.89 (Secondary malignant neoplasm of other digestive organs) compared with C88.00 (Waldenström macroglobulinemia not having achieved remission), from the official CMS tabular data. Both may be reported when both conditions are documented (Excludes2).

Can these codes be reported together?

Yes, when both are documented. C88.00 carries an Excludes2 note covering C78.89: “secondary neoplasm of spleen (C78.89)”

Excludes2 marks distinct conditions — both may be reported when both are documented.

Side by side

C78.89Secondary malignant neoplasm of other digestive organsC88.00Waldenström macroglobulinemia not having achieved remission
Billing statusBillableBillable
ClassificationC00-D49 — Neoplasms (C00-D49)C00-D49 — Neoplasms (C00-D49)
DefinitionSecondary malignant neoplasm of other digestive organs is a billable ICD-10-CM diagnosis code (C78.89).Waldenström macroglobulinemia not having achieved remission is a billable ICD-10-CM diagnosis code (C88.00).
Includes
Lymphoplasmacytic lymphoma with IgM-production, NOS
Lymphoplasmacytic lymphoma with IgM-production not having achieved remission
Lymphoplasmacytic lymphoma with IgM-production with failed remission
Macroglobulinemia (idiopathic) (primary) NOS

Derived from the official CMS ICD-10-CM tabular data (FY2026). Not billing advice; verify sequencing rules for the encounter. All data sources